Restricted maximum likelihood

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In

maximum likelihood estimation that does not base estimates on a maximum likelihood fit of all the information, but instead uses a likelihood function calculated from a transformed set of data, so that nuisance parameters have no effect.[1]

In the case of

maximum likelihood estimation, REML can produce unbiased estimates of variance and covariance parameters.[2]

The idea underlying REML estimation was put forward by M. S. Bartlett in 1937.[1][3] The first description of the approach applied to estimating components of variance in unbalanced data was by Desmond Patterson and Robin Thompson[1][4] of the University of Edinburgh in 1971, although they did not use the term REML. A review of the early literature was given by Harville.[5]

REML estimation is available in a number of general-purpose

statistical software packages, including Genstat (the REML directive), SAS (the MIXED procedure), SPSS (the MIXED command), Stata (the mixed command), JMP (statistical software), and R (especially the lme4 and older nlme
packages), as well as in more specialist packages such as .

REML estimation is implemented in Surfstat, a

Matlab toolbox for the statistical analysis of univariate and multivariate surface and volumetric neuroimaging data using linear mixed effects models and random field theory,[6][7] but more generally in the fitlme package for modeling linear mixed effects models in a domain-general way.[8]

References