Ringer's solution

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Ringer's solution

Ringer's solution is a solution of several salts dissolved in water for the purpose of creating an

dextrose
, as well as antibiotics and antifungals.

Composition

Ringer's solution typically contains

osmoregulators.[1][2]

Uses

Ringer's solution is frequently administered to human and veterinary patients for intravenous or subcutaneous hydration and to expand the vascular compartment in hypovolemia. It is also use in in vitro experiments on organs or tissues, such as in vitro muscle testing.[3][4][5][6] The precise mix of ions can vary depending upon the taxon, with different recipes for birds, mammals, freshwater fish, marine fish, etc.

Ringers solution may also be used for therapeutic purposes, such as

intravenous infusion for replacing extracellular fluid losses and restoring chemical balances when treating isotonic dehydration.[9]

History

Ringer's solution is named after Sydney Ringer, who in 1882–1885 determined that a solution perfusing a frog's heart must contain sodium, potassium and calcium salts in a definite proportion if the heart is to be kept beating for long.[10][11] This solution was adjusted further in the 1930s by Alexis Hartmann, who added sodium lactate to form Ringer's lactate solution.[12]

References

  1. ^ "COMPENDIA NOTES, PART B: RINGER'S SOLUTIONS". Marine Biological Laboratory. Retrieved 10 June 2018.
  2. ^ "Table 3. Composition of Ringer's Solution". Research Gate. Retrieved 10 June 2018.
  3. ^ "What is Ringer's solution?". HydroTherapy. Retrieved 10 June 2018.
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  7. ^ "Clinical Management of Septic Arthritis in a Sheep: A Case Report". Advances in Animal and Veterinary Sciences. 5 (6): 267–270. July 2017.
  8. PMID 12472244
    .
  9. ^ "Ringers Solution for Infusion". Electronic Medicines Compendium. Retrieved 10 June 2018.
  10. ISBN 978-0-87893-322-8.{{cite book}}: CS1 maint: location (link
    )
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