SB-243213

SB-243213
Identifiers
	IUPAC name 5-methyl-N-(6-[(2-methylpyridin-3-yl)oxy]pyridin-3-yl)-6-(trifluoromethyl)indoline-1-carboxamide;
JSmol)	Interactive image;
	SMILES CC1=C(C(F)(F)F)C=C(N(C(NC2=CN=C(OC3=C(C)N=CC=C3)C=C2)=O)CC4)C4=C1;
	InChI InChI=1S/C22H19F3N4O2/c1-13-10-15-7-9-29(18(15)11-17(13)22(23,24)25)21(30)28-16-5-6-20(27-12-16)31-19-4-3-8-26-14(19)2/h3-6,8,10-12H,7,9H2,1-2H3,(H,28,30); Key:ZETBBVYSBABLHL-UHFFFAOYSA-N;

SB-243213 is a research chemical which acts as a selective

5HT_2C receptor and has anxiolytic effects. It has better than 100x selectivity for 5-HT_2C over all other receptor subtypes tested, and a longer duration of action compared to older 5-HT_2C antagonist ligands.^[1]^[2]^[3]^[4]^[5]^[6]^[7]^[8]

References

S2CID 36124035
.

S2CID 36766760
.

S2CID 29021463
.

S2CID 20866665
.

S2CID 14889900
.

PMID 17059817
.

PMID 18977370
.

PMID 22643326
.

v
t
e

Retrieved from "https://en.wikipedia.org/w/index.php?title=SB-243213&oldid=1198052804"

[1] S2CID 36124035
.

[2] S2CID 36766760
.

[3] S2CID 29021463
.

[4] S2CID 20866665
.

[5] S2CID 14889900
.

[6] PMID 17059817
.

[7] PMID 18977370
.

[8] PMID 22643326
.

[1]

[2]

[3]

[4]

[5]

[6]

[7]

[8]

See also

References