Scoulerine

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Scoulerine
Scoulerine
Names
IUPAC name
3,10-Dimethoxyberbine-2,9-diol
Systematic IUPAC name
(13aS)-3,10-Dimethoxy-5,8,13,13a-tetrahydro-6H-isoquinolino[3,2-a]isoquinoline-2,9-diol
Other names
(S)-Scoulerin; Discretamine; Aequaline
Identifiers
3D model (
JSmol
)
ChEBI
ChEMBL
ChemSpider
KEGG
  • InChI=1S/C19H21NO4/c1-23-17-4-3-11-7-15-13-9-16(21)18(24-2)8-12(13)5-6-20(15)10-14(11)19(17)22/h3-4,8-9,15,21-22H,5-7,10H2,1-2H3/t15-/m0/s1 checkY
    Key: KNWVMRVOBAFFMH-HNNXBMFYSA-N checkY
  • Oc1c4c(ccc1OC)C[C@H]3c2c(cc(OC)c(O)c2)CCN3C4
Properties
C19H21NO4
Molar mass 327.380 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)

Scoulerine, also known as discretamine and aequaline, is a

opium poppy,[2] Croton flavens,[3] and certain plants in the genus Erythrina.[4]

Studies show that scoulerine is an

adrenoceptor and 5-HT receptor.[5][6] It has also been found to be a GABAA receptor agonist in vitro.[3][7]

References

  1. PMID 26384972
    .
  2. S2CID 38780571
    .
  3. ^
    S2CID 13192928
    .
  4. PMID 10375996
    .
  5. PMID 7902181
    .
  6. PMID 7952879
    .
  7. S2CID 260282359
    .
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