De Bruijn graph: Difference between revisions

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|author1=de Bruijn |author2=N. G. | authorlink = Nicolaas Govert de Bruijn
|author1=de Bruijn |author2=N. G. | authorlink = Nicolaas Govert de Bruijn
| title = A Combinatorial Problem
| title = A Combinatorial Problem
| journal = Koninklijke Nederlandse Akademie v. Wetenschappen
| journal = Koninklijke Nederlandse Akademie V. Wetenschappen
| volume = 49
| volume = 49
| pages = 758–764
| pages = 758–764
Line 139: Line 139:
| title = On the representation of de Bruijn graphs
| title = On the representation of de Bruijn graphs
| year = 2014
| year = 2014
| arxiv = 1401.5383}}
| eprint = 1401.5383| class = q-bio.QM
}}
</ref>
</ref>
</references>
</references>

Revision as of 11:48, 7 February 2019

In graph theory, an n-dimensional De Bruijn graph of m symbols is a directed graph representing overlaps between sequences of symbols. It has mn vertices, consisting of all possible length-n sequences of the given symbols; the same symbol may appear multiple times in a sequence. If we have the set of m symbols then the set of vertices is:

If one of the vertices can be expressed as another vertex by shifting all its symbols by one place to the left and adding a new symbol at the end of this vertex, then the latter has a directed edge to the former vertex. Thus the set of arcs (aka directed edges) is

Although De Bruijn graphs are named after Nicolaas Govert de Bruijn, they were discovered independently by both De Bruijn[1] and I. J. Good.[2] Much earlier, Camille Flye Sainte-Marie[3] implicitly used their properties.

Properties

  • If then the condition for any two vertices forming an edge holds vacuously, and hence all the vertices are connected forming a total of edges.
  • Each vertex has exactly incoming and outgoing edges.
  • Each -dimensional De Bruijn graph is the line digraph of the -dimensional De Bruijn graph with the same set of symbols.[4]
  • Each De Bruijn graph is
    Hamiltonian. The Euler cycles and Hamiltonian cycles of these graphs (equivalent to each other via the line graph construction) are De Bruijn sequences
    .

The line graph construction of the three smallest binary De Bruijn graphs is depicted below. As can be seen in the illustration, each vertex of the -dimensional De Bruijn graph corresponds to an edge of the -dimensional De Bruijn graph, and each edge in the -dimensional De Bruijn graph corresponds to a two-edge path in the -dimensional De Bruijn graph.

Dynamical systems

Binary De Bruijn graphs can be drawn (below, left) in such a way that they resemble objects from the theory of

Lorenz attractor
(below, right):

       

This analogy can be made rigorous: the n-dimensional m-symbol De Bruijn graph is a model of the

Bernoulli map

The Bernoulli map (also called the

m-adic number.[5] The trajectories of this dynamical system correspond to walks in the De Bruijn graph, where the correspondence is given by mapping each real x in the interval [0,1) to the vertex corresponding to the first n digits in the base-m representation of x. Equivalently, walks in the De Bruijn graph correspond to trajectories in a one-sided subshift of finite type
.

Directed graphs of two B (2, 3) de Bruijn sequences and a B (2, 4) sequence. In B(2,3). each vertex is visited once, whereas in B(2,4), each edge is traversed once.

Uses

See also

References

  1. ^ de Bruijn; N. G. (1946). "A Combinatorial Problem". Koninklijke Nederlandse Akademie V. Wetenschappen. 49: 758–764.
  2. ^ .
  3. ^ Flye Sainte-Marie, C. (1894). "Question 48". L'Intermédiaire des Mathématiciens. 1: 107–110.
  4. ^ Zhang, Fu Ji; Lin, Guo Ning (1987). "On the de Bruijn-Good graphs". Acta Math. Sinica. 30 (2): 195–205.
  5. ^ Leroux, Philippe (2002), Coassociative grammar, periodic orbits and quantum random walk over Z,
  6. ^ Pevzner, Pavel A.; Tang, Haixu; Waterman, Michael S. (2001). "An Eulerian path approach to DNA fragment assembly". PNAS. 98 (17): 9748–9753.
    PMID 11504945
    .
  7. ^ Pevzner, Pavel A.; Tang, Haixu (2001). "Fragment Assembly with Double-Barreled Data". Bioinformatics. 1: 1–9. .
  8. ^ Zerbino, Daniel R.; Birney, Ewan (2008). "Velvet: algorithms for de novo short read assembly using de Bruijn graphs". Genome Research. 18 (5): 821–829.
    PMID 18349386
    .
  9. ^ Chikhi, R; Limasset, A; Jackman, S; Simpson, J; Medvedev, P (2014). "On the representation of de Bruijn graphs". ].

External links