Substrate adhesion molecules
Substrate adhesion molecules (SAMs) are
proteins that attach cells to specific compounds in the extracellular matrix (a process known as cell adhesion).[1]
Some of the
actin filaments in the cytoskeleton, while the other is connected to the SAMs. This enables external activity in the extracellular matrix to affect the shape and movement of the cell.[2]
SAMs do not have to be made by the cells that bind to them. They can also link to other SAMs, influencing each other's behavior.[3]
There is very strong evidence SAMs also have a key role in
neuronal morphogenesis.[4]
See also
- Cell adhesion molecules
- Fibronectin
- Laminin
References
- ISBN 978-3-540-66527-4.
- ISBN 978-1-56032-936-7.
- ISBN 978-0-8493-1567-1.
- ISBN 978-0-387-25615-3.
Further reading
- Ulrich, Klaus (1994). "Cell-Adhesion Molecules of Vertebrates". Comparative animal biochemistry. Springer. ISBN 978-3-540-57420-0.
- Haschek, Wanda M.; et al. (2009). Fundamentals of Toxicologic Pathology (2nd ed.). Academic Press. p. 635. ISBN 978-0-12-370469-6.
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