Talk:Epitope
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The contents of the Neoantigenic determinant page were merged into Epitope on 3 November 2017. For the contribution history and old versions of the redirected page, please see its history; for the discussion at that location, see its talk page. |
Wiki Education Foundation-supported course assignment
This article was the subject of a Wiki Education Foundation-supported course assignment, between 19 August 2020 and 4 December 2020. Further details are available on the course page. Student editor(s): MicrobiologyKat2020. Peer reviewers: MdMcAlister, SSalley2022.
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- An antigen must contain at least 2 epitopes.
I don't see why. An antibody typically binds two epitopes, but they can and usually do come from different antigen molecules. AxelBoldt 07:19, 20 December 2005 (UTC)
Totally correct Shaq141 22:02, 29 March 2006 (UTC)
Very true antigenic determinants can be merged with epitope.
I agree about the merging of the two pages as well. That's how they also thought us in class, in any case. (11-13-2007)
Re-balancing this article to cover both B and T cell epitopes
It has been ten years since I last did major edits on this page. Back then, there was a disbalance focusing on antibody epitopes. This has crept back over time. The term 'epitope' covers both T cell and antibody recognition targets. The first paragraph should focus on what is true for both, rather than giving examples that are only true for antibodies. Tellingly, in a recent edit the 'for example' preceding the statement that epitopes are bound by antibodies was replaced by 'in other words', making the entire section wrong. I reversed that edit, and would like to spend more quality time re-arranging the entire article, starting with a general description of epitopes and moving all bits with B cell and T cell specific information to subsequent sections. So this is a heads-up. Please do comment and use the talk page if I am messing things up. It has been a while since I edited wikipedia pages, but I do know a thing or two about epitopes(my google scholar profile). Bpeters (talk) 22:13, 19 May 2016 (UTC)
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2020 Revisions
Hello! I am working on this page as part of a cell biology honors project. I've added to the sections titled: Epitope Function, Epitope Mapping, and added a section called Epitope-based vaccines. I also reorganized the sections I edited so that they divided information up based on what's true for B-cell epitopes and T-cell epitopes. Please let me know if anything looks amiss and I'll try to fix it. Thanks! MicrobiologyKat2020 (talk) 15:38, 5 November 2020 (UTC)