Talk:Protein superfamily

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I've added examples to the section and tried to illustrate the structural conservation that allows superfamilies to be recognised. My background is in proteases so that's where I've drawn examples from. Examples from other superfamilies would help balance it out a bit. T. Shafee (Evo&Evo) (talk) 14:36, 27 October 2013 (UTC)[reply]

Since the topic is of high importance to both computational, evolutionary and molecular biology, It really should be of class A standard. Here are my suggestions for how to get there:

• Clear definition(s) of a superfamily, what different ones are being used?
• A wider set of examples
• An expansion of the evolutionary significance to include discussion of why some superfamilies are so over-represented in nature
• Something on the evolutionary processes that underlie:
  • the diversification of superfamilies
  • the de novo generation of new protein folds

Any other ideas welcome. T. Shafee (Evo&Evo) (talk) 14:21, 30 October 2013 (UTC)[reply]

Approximately how many superfamilies have currently been identified? Just an order of magnitude estimate would already be a significant improvement to the article. ◅ Sebastian 02:48, 4 September 2020 (UTC)[reply]