Talk:Substance P
| This is the talk page for discussing improvements to the Substance P article. This is not a forum for general discussion of the article's subject. |
Article policies
|
| Find sources: Google (books · news · scholar · free images · WP refs) · FENS · JSTOR · TWL |
Archives: 1Auto-archiving period: 1095 days  |
chemicals. To participate, help improve this article or visit the project page for details on the project. | ||
| Low | This article has been rated as Low-importance on the project's importance scale. | |
Molecular Biology on Wikipedia. If you would like to participate, please visit the project page, where you can join the discussion and see a list of open tasks. | ||
| ??? | This article has not yet received a rating on the importance scale. | |
 | This article is supported by the Molecular and Cell Biology task force (assessed as Low-importance). | |
 | Pharmacology High‑importance | ||||||
| |||||||
PMID 24705689 - Involvement of substance P and the NK-1 receptor in human pathology.
Muñoz M1, Coveñas R.
Amino Acids. 2014 Jul;46(7):1727-50.
doi: 10.1007/s00726-014-1736-9.
Epub 2014 Apr 6.
PMID 24705689
Involvement of substance P and the NK-1 receptor in human pathology.
Abstract [excerpt]
- The peptide substance P (SP) .... . After binding to the neurokinin-1 (NK-1) receptor, SP regulates many pathophysiological functions in the central nervous system, such as emotional behavior, stress, depression, anxiety, emesis, vomiting, migraine, alcohol addiction, seizures and neurodegeneration. SP has been also implicated in pain, inflammation, hepatitis, hepatotoxicity, cholestasis, pruritus, myocarditis, bronchiolitis, abortus, bacteria and viral infection (e.g., HIV infection) and it plays an important role in cancer (e.g., tumor cell proliferation, antiapoptotic effects in tumor cells, angiogenesis, migration of tumor cells for invasion, infiltration and metastasis). ...
PMID 24705689
[PubMed - in process]