Estrone:Estradiol (E2:E1) Ratio

A large amount of estradiol consumed sublingually, and especially

competitive antagonism. but a high estrone ratio is linked to reduced skeletal growth in pubertal boys and insulin resistance in PCOS.^[2]^[3] ^[4]

The ratio is also known to be higher in early female puberty, and lower in the later stages.

ISSN 2688-4887
.

^ Kvernebo-Sunnergren, Kjersti; Ankarberg-Lindgren, Carina; AEkesson, Karin; Dahlgren, Jovanna (2016-08-19). "Correlations between Prepubertal and Pubertal Estrogen Levels and Final Height Out-Come in Growth Hormone (GH) Treated Boys with Silver Russell syndrome". ESPE Abstracts. 86. Bioscientifica.

^ Kim, Nayoung; Chun, Sungwook (2021 Dec 1.). "Association between the serum estrone-to-estradiol ratio and parameters related to glucose metabolism and insulin resistance in women with polycystic ovary syndrome". Clinical and Experimental Reproductive Medicine – via NCBI. {{cite journal}}: Check date values in: |date= (help)

ISSN 2051-817X. {{cite journal}}: Check date values in: |date= (help
)

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[1] ISSN 2688-4887
.

[2] Kvernebo-Sunnergren, Kjersti; Ankarberg-Lindgren, Carina; AEkesson, Karin; Dahlgren, Jovanna (2016-08-19). "Correlations between Prepubertal and Pubertal Estrogen Levels and Final Height Out-Come in Growth Hormone (GH) Treated Boys with Silver Russell syndrome". ESPE Abstracts. 86. Bioscientifica.

[3] Kim, Nayoung; Chun, Sungwook (2021 Dec 1.). "Association between the serum estrone-to-estradiol ratio and parameters related to glucose metabolism and insulin resistance in women with polycystic ovary syndrome". Clinical and Experimental Reproductive Medicine – via NCBI. {{cite journal}}: Check date values in: |date= (help)

[4] ISSN 2051-817X. {{cite journal}}: Check date values in: |date= (help
)

[2]

[3]

[4]