Voxtalisib

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Voxtalisib
Identifiers
  • 2-amino-8-ethyl-4-methyl-6-(1H-pyrazol-5-yl)pyrido[2,3-d]pyrimidin-7-one
JSmol)
  • CCN1C2=NC(=NC(=C2C=C(C1=O)C3=CC=NN3)C)N
  • InChI=1S/C13H14N6O/c1-3-19-11-8(7(2)16-13(14)17-11)6-9(12(19)20)10-4-5-15-18-10/h4-6H,3H2,1-2H3,(H,15,18)(H2,14,16,17)
  • Key:RGHYDLZMTYDBDT-UHFFFAOYSA-N

Voxtalisib (XL-765, SAR245409) is a drug which acts as a dual

mechanistic target of rapamycin (mTOR). It is in clinical trials for the treatment of various types of cancer.[1][2][3][4][5]

References

  1. PMID 21317208
    .
  2. S2CID 23993969
    .
  3. PMID 29550382
    .
  4. PMID 31247018
    .
  5. PMID 32033478
    .
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