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There is a page named "Zone of polarizing activity" on Wikipedia

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  • Thumbnail for Zone of polarizing activity
    The zone of polarizing activity (ZPA) is an area of mesenchyme that contains signals which instruct the developing limb bud to form along the anterior/posterior...
    15 KB (2,075 words) - 12:02, 28 December 2024
  • Thumbnail for Polydactyly in stem-tetrapods
    Polydactyly in stem-tetrapods (category Evolution of tetrapods)
    called the ZRS (zone of polarizing region activity regulatory sequence) that is located approximately 1 Mb upstream of the coding sequence of Shh." Devonian...
    9 KB (993 words) - 12:15, 6 September 2024
  • Thumbnail for Polydactyl cat
    Polydactyl cat (category Congenital disorders of musculoskeletal system)
    expression of SHH is seen on the anterior side of the limb. Normally SHH is expressed in an organiser region, called the zone of polarizing activity (ZPA)...
    17 KB (1,902 words) - 17:20, 15 January 2025
  • Thumbnail for Limb development
    the zone of polarizing activity (ZPA) with the mesenchymal cells. In addition to the dorsal-ventral axis created by the ectodermal expression of competitive...
    36 KB (4,234 words) - 05:17, 25 June 2025
  • Thumbnail for Limb bud
    (AER) and the zone of polarizing activity (ZPA) with the mesenchymal cells. These signaling centers are crucial to the proper formation of a limb that is...
    24 KB (2,943 words) - 19:33, 27 May 2025
  • Domestication of the chicken)
    using chicken embryos, such as the discovery of the apical ectodermal ridge and the zone of polarizing activity. The chicken was the first bird species to...
    70 KB (6,574 words) - 19:23, 28 June 2025
  • Thumbnail for Polydactyly
    Polydactyly (category Congenital disorders of musculoskeletal system)
    1Mb upstream of SHH gene has been implicated. Normally SHH is expressed in an organiser region, called the zone of polarizing activity (ZPA) on the posterior...
    63 KB (7,279 words) - 08:46, 1 July 2025
  • Thumbnail for Sonic hedgehog protein
    digits depends on the secretion of sonic hedgehog by the zone of polarizing activity, located on the posterior side of the embryonic limb bud. Mutations...
    63 KB (7,452 words) - 18:46, 28 May 2025
  • Thumbnail for Regulation of gene expression
    generation of the hand (digits - interdigits): the gradient of sonic hedgehog (secreted inducing factor) from the zone of polarizing activity in the limb...
    45 KB (5,236 words) - 08:15, 27 June 2025
  • Thumbnail for Origin of birds
    of bird digits as I, II, III (as in their theropod ancestors) due to the posterior finger's development outside the shh-expressing zone of polarizing...
    114 KB (12,002 words) - 12:45, 30 June 2025
  • Thumbnail for Acheiropodia
    Acheiropodia (category Congenital disorders of musculoskeletal system)
    they help an enhancer called ZRS (zone of polarizing activity regulatory sequence), which is found in intron 5 of the LMBR1 gene, interact with the Sonic...
    20 KB (2,112 words) - 04:44, 2 June 2025
  • diffusible factor produced by the zone of polarizing activity (ZPA), a small region of tissue at the posterior margin of the limb. Mammalian development appeared...
    59 KB (6,910 words) - 21:16, 5 May 2025
  • Thumbnail for T-box
    Ultimately, TBX4 and TBX5 lead to the development of apical ectodermal ridge (AER) and zone of polarizing activity (ZPA) signaling centers in the developing limb...
    10 KB (1,078 words) - 02:06, 8 January 2025
  • Thumbnail for TBX5 (gene)
    Ultimately, Tbx5 leads to the development of apical ectodermal ridge (AER) and zone of polarizing activity (ZPA) signaling centers in the developing limb...
    21 KB (2,467 words) - 00:51, 20 June 2025
  • Ultimately, Tbx4 leads to the development of apical ectodermal ridge (AER) and zone of polarizing activity (ZPA) signaling centers in the developing limb...
    14 KB (1,577 words) - 04:57, 5 February 2025
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