ACSL5
| ACSL5 | |||
|---|---|---|---|
| Identifiers | |||
Gene ontology | |||
| Molecular function | |||
| Cellular component | |||
| Biological process | |||
| Sources:Amigo / QuickGO | |||
Ensembl | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| UniProt | |||||||||
| RefSeq (mRNA) | |||||||||
| RefSeq (protein) | |||||||||
| Location (UCSC) | Chr 10: 112.37 – 112.43 Mb | Chr 19: 55.24 – 55.29 Mb | |||||||
| PubMed search | [3] | [4] | |||||||
| View/Edit Human | View/Edit Mouse |
Long-chain-fatty-acid—CoA ligase 5 is an enzyme that in humans is encoded by the ACSL5 gene.[5][6]
The protein encoded by this gene is an
isoforms have been found for this gene.[6]
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000197142 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000024981 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- PMID 11127823.
- ^ a b "Entrez Gene: ACSL5 acyl-CoA synthetase long-chain family member 5".
External links
- Human ACSL5 genome location and ACSL5 gene details page in the UCSC Genome Browser.
Further reading
- Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. PMID 8125298.
- Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. PMID 9373149.
- Lewin TM, Kim JH, Granger DA, et al. (2001). "Acyl-CoA synthetase isoforms 1, 4, and 5 are present in different subcellular membranes in rat liver and can be inhibited independently". J. Biol. Chem. 276 (27): 24674–9. PMID 11319232.
- Minekura H, Kang MJ, Inagaki Y, et al. (2002). "Genomic organization and transcription units of the human acyl-CoA synthetase 3 gene". Gene. 278 (1–2): 185–92. PMID 11707336.
- Lewin TM, Van Horn CG, Krisans SK, Coleman RA (2002). "Rat liver acyl-CoA synthetase 4 is a peripheral-membrane protein located in two distinct subcellular organelles, peroxisomes, and mitochondrial-associated membrane". Arch. Biochem. Biophys. 404 (2): 263–70. PMID 12147264.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. PMID 12477932.
- Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. PMID 12975309.
- Gassler N, Schneider A, Kopitz J, et al. (2003). "Impaired expression of acyl-CoA-synthetase 5 in epithelial tumors of the small intestine". Hum. Pathol. 34 (10): 1048–52. PMID 14608540.
- Deloukas P, Earthrowl ME, Grafham DV, et al. (2004). "The DNA sequence and comparative analysis of human chromosome 10". Nature. 429 (6990): 375–81. PMID 15164054.
- Mashek DG, Bornfeldt KE, Coleman RA, et al. (2005). "Revised nomenclature for the mammalian long-chain acyl-CoA synthetase gene family". J. Lipid Res. 45 (10): 1958–61. PMID 15292367.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. PMID 15489334.
- Gassler N, Obermüller N, Keith M, et al. (2005). "Characterization of metaplastic and heterotopic epithelia in the human gastrointestinal tract by the expression pattern of acyl-CoA synthetase 5". Histol. Histopathol. 20 (2): 409–14. PMID 15736044.
- Obermüller N, Keith M, Kopitz J, et al. (2006). "Coeliac disease is associated with impaired expression of acyl-CoA-synthetase 5". International Journal of Colorectal Disease. 21 (2): 130–4. S2CID 24263574.
- Achouri Y, Hegarty BD, Allanic D, et al. (2006). "Long chain fatty acyl-CoA synthetase 5 expression is induced by insulin and glucose: involvement of sterol regulatory element-binding protein-1c". Biochimie. 87 (12): 1149–55. PMID 16198472.
- Adamo KB, Dent R, Langefeld CD, et al. (2007). "Peroxisome proliferator-activated receptor gamma 2 and acyl-CoA synthetase 5 polymorphisms influence diet response". Obesity. 15 (5): 1068–75. S2CID 1525140.
- Gassler N, Roth W, Funke B, et al. (2007). "Regulation of enterocyte apoptosis by acyl-CoA synthetase 5 splicing". Gastroenterology. 133 (2): 587–98. PMID 17681178.
- Zhou Y, Abidi P, Kim A, et al. (2007). "Transcriptional activation of hepatic ACSL3 and ACSL5 by oncostatin m reduces hypertriglyceridemia through enhanced beta-oxidation". Arterioscler. Thromb. Vasc. Biol. 27 (10): 2198–205. PMID 17761945.
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