ARHGAP4

ARHGAP4
Available structures
Gene ontology
Molecular function	protein binding; GTPase activator activity; identical protein binding;
Cellular component	cytosol; Golgi apparatus; growth cone; microtubule; cytoplasm;
Biological process	negative regulation of fibroblast migration; nervous system development; positive regulation of GTPase activity; negative regulation of cell migration; cytoskeleton organization; Rho protein signal transduction; regulation of small GTPase mediated signal transduction; negative regulation of axon extension; signal transduction; positive regulation of signal transduction;
	Sources:Amigo / QuickGO
	ENSG00000089820
	ENSMUSG00000031389
	P98171
	n/a
	NM_001666; NM_001164741
	NM_001162423; NM_001162424; NM_138630
	NP_001158213; NP_001657
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Rho GTPase-activating protein 4 is an

cell motility and axonal outgrowth in vitro.^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000089820 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000031389 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
PMID 8570618
.

^ "Entrez Gene: ARHGAP4 Rho GTPase activating protein 4".

PMID 17804252.{{cite journal}}: CS1 maint: numeric names: authors list (link
)

External links

Human ARHGAP4 genome location and ARHGAP4 gene details page in the UCSC Genome Browser.

Further reading

Tribioli C, Mancini M, Plassart E, et al. (1995). "Isolation of new genes in distal Xq28: transcriptional map and identification of a human homologue of the ARD1 N-acetyl transferase of Saccharomyces cerevisiae". Hum. Mol. Genet. 3 (7): 1061–7.
PMID 7981673
.

Nagase T, Seki N, Tanaka A, et al. (1996). "Prediction of the coding sequences of unidentified human genes. IV. The coding sequences of 40 new genes (KIAA0121-KIAA0160) deduced by analysis of cDNA clones from human cell line KG-1". DNA Res. 2 (4): 167–74, 199–210.
PMID 8590280
.

Brenner V, Nyakatura G, Rosenthal A, Platzer M (1997). "Genomic organization of two novel genes on human Xq28: compact head to head arrangement of IDH gamma and TRAP delta is conserved in rat and mouse". Genomics. 44 (1): 8–14.
PMID 9286695
.

Zuber J, Tchernitsa OI, Hinzmann B, et al. (2000). "A genome-wide survey of RAS transformation targets". Nat. Genet. 24 (2): 144–52.
S2CID 21887748
.

Hartley JL, Temple GF, Brasch MA (2001). "DNA Cloning Using In Vitro Site-Specific Recombination". Genome Res. 10 (11): 1788–95.
PMID 11076863
.

Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92.
PMID 11256614
.

Demura M, Takeda Y, Yoneda T, et al. (2002). "Two novel types of contiguous gene deletion of the AVPR2 and ARHGAP4 genes in unrelated Japanese kindreds with nephrogenic diabetes insipidus". Hum. Mutat. 19 (1): 23–9.
S2CID 21379792
.

Christerson LB, Gallagher E, Vanderbilt CA, et al. (2002). "p115 Rho GTPase activating protein interacts with MEKK1". J. Cell. Physiol. 192 (2): 200–8.
S2CID 33717402
.

Foletta VC, Brown FD, Young WS (2003). "Cloning of rat ARHGAP4/C1, a RhoGAP family member expressed in the nervous system that colocalizes with the Golgi complex and microtubules". Brain Res. Mol. Brain Res. 107 (1): 65–79.
PMID 12414125
.

Soderling SH, Binns KL, Wayman GA, et al. (2003). "The WRP component of the WAVE-1 complex attenuates Rac-mediated signalling". Nat. Cell Biol. 4 (12): 970–5.
S2CID 1423222
.

Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903.
PMID 12477932
.

Katoh M, Katoh M (2004). "FNBP2 gene on human chromosome 1q32.1 encodes ARHGAP family protein with FCH, FBH, RhoGAP and SH3 domains". Int. J. Mol. Med. 11 (6): 791–7.
PMID 12736724
.

Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to Biology: A Functional Genomics Pipeline". Genome Res. 14 (10B): 2136–44.
PMID 15489336
.

Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8.
PMID 16381901
.

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[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000089820 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000031389 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8570618-5] PMID 8570618
.

[entrez-6] "Entrez Gene: ARHGAP4 Rho GTPase activating protein 4".

[7] PMID 17804252.{{cite journal}}: CS1 maint: numeric names: authors list (link
)

[3]

[4]

[7]