ATCC (company)

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American Type Culture Collection
Established1925
HeadquartersManassas, Virginia
Websiteatcc.org

ATCC or the American Type Culture Collection is a

cell lines and other materials for research and development. Established in 1925 to serve as a national center for depositing and distributing microbiological specimens, ATCC has since grown to distribute in over 150 countries.[1][2] It is now the largest general culture collection in the world.[3]

Products and collections

ATCC's collections include a wide range of biological materials for research, including cell lines, microorganisms and

hybridomas.[3] ATCC's microorganism collection includes a collection of more than 18,000 strains of bacteria, as well as 3,000 different types of animal viruses and 1,000 plant viruses. In addition, ATCC maintains collections of protozoans, yeasts and fungi with over 7,500 yeast and fungus species and 1,000 strains of protists.[3][1]

Services

In addition to serving as a biorepository and distributor, ATCC provides specialized services as a biological resource center. Individuals and groups can employ a safe deposit service for their own cell cultures, providing a secure back-up for valuable biomaterials if required. ATCC also is able to retain secure samples of patented materials and distribute them according to instructions and approval of the patent holder. ATCC also provides biological repository management services to institutions, agencies and companies wishing to outsource the handling of their own culture collections.[3] ATCC also manages BEI Resources, who provides reagents, tools and information needed in research on microbes.[4]

ATCC also serves to set standards for biological reagent and assay quality. These standards are used by the

forensic
information.

Facilities

ATCC headquarters and production facilities are based in a 126,000 sq ft (11,700 m2) building in

Manassas, Virginia. This includes the 18,000 sq ft (1,700 m2) biological material repository which contains 200 freezers to store biomaterials, including vapor-phase liquid nitrogen freezers, mechanical freezers, and cold rooms for storage at 4 °C. Electricity at the repository is backed up by on-site generators. The facility also includes 35,000 sq ft (3,300 m2) of laboratory space.[1]

Databases

ATCC has created and continues to maintain several public

type-strains.[8] In 2022, ATCC entered into a partnership with QIAGEN to create a commercial database of RNA-seq data produced by ATCC for all human and animal cell lines held within ATCC's biorepository.[9]

Customers

ATCC products and services are used both nationally and internationally by researchers in academia and government, as well as private industry. Over 80% of ATCC’s customers come from academia and industry – 42% from universities and colleges and 41% from private industry. Government customers comprise 6% of the organization’s total. Three-quarters of ATCC customers are from the United States, while the remaining 25% are international customers. ATCC maintains authorized distributors in Europe, Japan, Australia, New Zealand, Hong Kong, Singapore, South Korea, Israel, and Taiwan, and makes other international shipments directly from its Virginia facilities. Among the industries represented ATCC’s customer base are the pharmaceutical, biotechnology, agricultural and diagnostics industries, as well as food, beverage and cosmetics makers and reference and testing laboratories.[1]

The ATCC also has working links with several other international culture collections, such as the UK's

Deutsche Sammlung von Mikroorganismen und Zellkulturen
(DSMZ, or German Collection of Microorganisms and Cell Cultures), the Japanese Collection of Research Bioresources (JCRB), and others.

Controversy

ATCC, along with the

Charles Duelfer.[11]

References

  1. ^ a b c d "Who We Are". ATCC. Retrieved 2 February 2018.
  2. ^ Clark, W.A. and D. H. Geary. 1974. The Story of the American Type Culture Collection – Its History and Development (1899-1973). Advances in Applied Microbiology 17:295-309.
  3. ^ a b c d Berns KI; Bond EC; Manning FJ, eds. (1996). "The American Type Culture Collection". Resource Sharing in Biomedical Research. Washington, D.C.: National Academies Press (US). Retrieved 14 May 2016.
  4. ^ "You are being redirected..." www.mlo-online.com. Retrieved 2018-12-14.
  5. ^ FDA (CFR 172, 173, 436, 444, 455, 460, 610); USP (Chapters: 51,61,62, 63, 71,81,91, 115, 171, 1035, 1046, 1072,1211, 2021)
  6. ^ "American Type Culture Collection (ATCC) Signs CRADA With NIST To Validate Genetic Identification Technique For Mouse Cell Lines". BioSpace. Retrieved 2023-04-19.
  7. ^ "ATCC launches first portal of whole-genome sequences based on authenticated biological standards". The Scientist Magazine®. Retrieved 2023-04-19.
  8. ^ "Genomes". ATCC Genome Portal. Retrieved 2023-04-19.
  9. ^ "ATCC Announces Expansion of its Bioinformatics Data Platform with QIAGEN". www.businesswire.com. 2022-04-04. Retrieved 2023-04-19.
  10. ^ "Iraq got seeds for bioweapons from U.S." Baltimore Sun. Associated Press. October 1, 2002. Archived from the original on January 2, 2007. Retrieved 2006-06-09.
  11. ^ Duelfer, Charles. Comprehensive Report of the Special Advisor to the Director of Central Intelligence on Iraq's Weapons of Mass Destruction Archived October 15, 2012, at the Wayback Machine, 30 September 2004, Vol 3, "Biological Warfare", p.21.

External links

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