Catherine Nobes

Add links
Source: Wikipedia, the free encyclopedia.
Catherine D. Nobes
Catherine Nobes
Born (1964-04-01) 1 April 1964 (age 60)
Alma materUniversity College London
University of London
Scientific career
InstitutionsUniversity College London
University of Bristol

Catherine D. Nobes (born 1 April 1964) is a Professor of Cell Biology and Head of School of Biochemistry at the

Eph receptors
.

Early life and education

Nobes went to school at Windsor Girls' School and was a county level high jumper as a teenager[citation needed]. She studied biochemistry at the University of London.[1] She completed a PhD at the University of Cambridge, working with Martin Brand. Nobes did brief Post-Docs in Helen Saibil and Aviva Tolkovsky's labs in Oxford before joining Alan Hall's laboratory at the University College London, where she identified the role of the GTPase CDC42 and effectors in forming actin-rich filopodial extensions.[1][2] She investigated the regulation of actin polymerisation and how cell movement determines polarity and adhesion.[3][4] She was awarded a Lister Institute of Preventive Medicine Fellowship in 2007, which allowed her to study cell migration in the context of axonal guidance and cancer metastasis.[1][5]

Research and career

Nobes was awarded a Medical Research Council Fellowship at University College London in 2001, where she worked in the Laboratory for Molecular Cell Biology (LMCB).[1][6] Her work was featured in a Wellcome Trust exhibition of art and science, Growth and Form.[7][8] She joined the University of Bristol as a Reader in 2006, and was promoted to a Professor of Cell Biology in 2012.[1] She delivered her inaugural lecture in 2014, discussing cell migration and metastasis of cancer cells.[9] Since 2014 she has been the head of the School of Biochemistry, the first woman to do so in the School's 50-year history.

Her work largely considers the social behaviour of

metastatic prostate cancer cells, EphB receptors are misregulated in ways that might lead to cancer cell invasion / metastasis.[10]
She showed that similar activation of Eph signalling may underpin epithelial cell loosening during wound healing.

Academic service

Nobes has served on the grant allocation board of the Royal Society.[13] She was the editor of the British Society for Cell Biology newsletter.[14] In 2018 she joined the Advisory Committee of the Lister Institute of Preventive Medicine.[15]

References

  1. ^ a b c d e Bristol, University of. "2014: outputurl-86374-en. | School of Biochemistry | University of Bristol". www.bristol.ac.uk. Retrieved 2019-01-10.
  2. PMID 26089021
    .
  3. ISBN 9783319463711
    .
  4. PMID 10087266
    .
  5. ISBN 9780080496801
    .
  6. ^ UCL (2015-09-30). "Alumni". UCL. Retrieved 2019-01-10.
  7. ^ "Beautiful science inspires artists". 2001-02-28. Retrieved 2019-01-10.
  8. ISSN 1095-9203
    .
  9. ^ Bristol, University of. "Professor Kate Nobes - inaugural lecture | Public and Ceremonial Events Office | University of Bristol". www.bristol.ac.uk. Retrieved 2019-01-10.
  10. ^ a b c Bristol, University of. "Professor Catherine Nobes - Biochemistry". www.bris.ac.uk. Retrieved 2019-01-10.
  11. PMID 23495724
    .
  12. PMID 28171762
    .
  13. ^ "Kate Nobes | Royal Society". royalsociety.org. Retrieved 2019-01-10.
  14. ^ administrator. "BSCB Newsletter, Winter 2013 | British Society for Cell Biology". Retrieved 2019-01-10.
  15. ^ "The New Lister Institute Scientific Advisory Committee". Lister Institute. 2018-05-20. Retrieved 2019-01-10.
Retrieved from "https://en.wikipedia.org/w/index.php?title=Catherine_Nobes&oldid=1193253486"