Cephaeline
Names | |
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IUPAC name
7′,10,11-Trimethoxyemetan-6′-ol
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Systematic IUPAC name
(1R)-1-{[(2S,3R,11bS)-3-Ethyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-yl]methyl}-7-methoxy-1,2,3,4-tetrahydroisoquinolin-6-ol | |
Other names
Cepheline; Desmethylemetine; Dihydropsychotrine
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Identifiers | |
3D model (
JSmol ) |
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ChEMBL | |
ChemSpider | |
ECHA InfoCard
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100.006.902 |
KEGG | |
PubChem CID
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UNII | |
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Properties | |
C28H38N2O4 | |
Molar mass | 466.622 g·mol−1 |
Appearance | White silky crystals |
Solubility in ethanol | Soluble[vague] |
Hazards | |
Occupational safety and health (OHS/OSH): | |
Main hazards
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Emetic / poisonous |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Cephaeline is an
Psychotria acuminata.[1] Cephaeline induces vomiting by stimulating the stomach lining and is found in commercial products such as syrup of ipecac.[2] Chemically, it is closely related to emetine
.
Poison treatment
Cephaeline in the form of syrup of ipecac was once commonly recommended as an emergency treatment for accidental poisoning, but its use has been phased out due to its ineffectiveness.[3]
References
- ^ Lara, Alfonso; Valverde, Roberto; Gomez, Luis; Hidalgo, Nancy (July 1, 2003). "Micropropagacion de la planta medicinal psychotria acuminata". Agronomía Costarricense. Retrieved 26 December 2009.
- ^ "Pharma Japan: Approval of 4 drugs including Seroquel recommended: CPAC panel". Chemical Business Newsbase. November 14, 2000. Retrieved 26 December 2009.
- PMID 14595067.