Christina Curtis

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Christina Curtis
Curtis in 2021
Alma materUniversity of California, Los Angeles
Heidelberg University
University of Southern California
Scientific career
FieldsCancer genomics
Tumor evolution
Computational biology
Early detection[1]
InstitutionsStanford University
University of Cambridge
ThesisAnalysis of high-density oligonucleotide gene expression data for dissecting aging pathways (2007)
Doctoral advisorSimon Tavaré[2]
Websiteprofiles.stanford.edu/christina-curtis Edit this at Wikidata

Christina Curtis is an American scientist who is a Professor of Medicine, Genetics and Biomedical Data Science and an Endowed Scholar at

.

Early life and education

Curtis decided that she wanted to work on cancer treatments when she was a teenager.

PhD in molecular and computational biology in 2007 supervised by Simon Tavaré.[2][9]

Research and career

Curtis was a postdoctoral researcher at the University of Cambridge, where she spent three years before returning to the faculty at the University of Southern California.[citation needed]

Curtis has leveraged computational modeling to better understand

Systems Biology
group.

Curtis uses computer simulations to understand genetic mutations in tumor samples.[11] She believes that breast cancer tumors have genetic differences that respond differently to treatments.[11] In 2019, she combined molecular analysis and historical clinical data to create the largest breast cancer cohort. In this cohort she found four groups of tumors that occur later in life, up to 20 years after the initial cancer diagnosis. She also found a subset of breast cancer tumors that do not recur after five years.[12] To this end, Curtis believes that tumors with metastatic potential have this from the start – they are "born to be bad".[5]

In 2022, Curtis was appointed director of

Artificial Intelligence and Cancer Genomics at the Stanford Cancer Institute.[citation needed
]

Awards and honors

Selected publications

  • Curtis C; Shah SP; Chin SF; et al. (18 April 2012). "The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups".
    Wikidata Q29614700
    .
  • Jae-Ho Cheong (11 September 2014). "Comprehensive molecular characterization of gastric adenocarcinoma".
    Wikidata Q28244985
    .
  • Andrea Sottoriva; Haeyoun Kang; Zhicheng Ma; et al. (9 February 2015). "A Big Bang model of human colorectal tumor growth".
    Wikidata Q36074227
    .

References

  1. ^ a b Christina Curtis publications indexed by Google Scholar Edit this at Wikidata
  2. ^ a b Christina Curtis at the Mathematics Genealogy Project Edit this at Wikidata
  3. ^ Christina Curtis publications from Europe PubMed Central
  4. Wikidata Q92858397
    .
  5. ^ a b "Christina Curtis, PhD, MSc: Researching Ways to Intercept Cancer at Its Earliest Stages". aacr.org. American Association for Cancer Research. Retrieved 2023-05-09.
  6. ^ Christina Curtis on LinkedIn Edit this at Wikidata
  7. ^ "Christina Curtis". med.stanford.edu. Stanford Medicine. Retrieved 2023-05-09.
  8. ProQuest 304825898
    .
  9. ^ a b "Christina Curtis". bcrf.org. Breast Cancer Research Foundation. 2014-06-24. Retrieved 2023-05-09.
  10. ^ "Meet the Team". med.stanford.edu. Retrieved 2023-05-09.
  11. ^ a b c "Pioneer Award Program - Program Highlights". commonfund.nih.gov. 2013-06-26. Retrieved 2023-05-09.
  12. PMID 30867590
    .
  13. ^ Fletcher, Alexandra (2012-10-30). "Christina Curtis wins young investigator award". stemcell.keck.usc.edu. University of Southern California. Retrieved 2023-05-09.
  14. ^ "Christina Curtis". nasonline.org. Retrieved 2023-05-09.
  15. ^ "Meet Our Scholars". komen.org. Susan G. Komen. Retrieved 2023-05-09.
  16. ^ Jarrett, Keke (2022-04-09). "AACR honors elite group with scientific achievement awards and lectureships". aacrmeetingnews.org. AACR Annual Meeting News. Retrieved 2023-05-09.