Chromosome 6 open reading frame 203
Appearance
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Identifiers | ||||||
Ensembl | ||||||
UniProt | ||||||
RefSeq (mRNA) | ||||||
RefSeq (protein) | ||||||
Location (UCSC) | Chr 6: 107.03 – 107.05 Mb | Chr 10: 43.4 – 43.42 Mb | ||||
PubMed search | [3] | [4] |
View/Edit Human | View/Edit Mouse |
Chromosome 6 open reading frame 203 is a protein that in humans is encoded by the C6orf203 gene. [5]
C6orf203 protein is reported to be localised to the mitochondria of eukaryotes and possess an evolutionarily conserved RNA-binding domain.[6][7]
One study propose C6orf203 to associate with mitochondrial RNA polymerase (POLRMT) and increase mitochondrial transcription to protect the cell from mitochondrial RNA loss during stress.[7] However, another study propose C6orf203 to associate with the mitoribosomal large subunit and regulate mitochondrial translation.[6]
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000130349 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000019797 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: Chromosome 6 open reading frame 203". Retrieved 2018-05-11.
- ^ PMID 31396629.
- ^ PMID 31226201.
Further reading