Chromosome 6 open reading frame 203

Source: Wikipedia, the free encyclopedia.
MTRES1
Identifiers
Ensembl
UniProt
RefSeq (mRNA)

NM_001142468
NM_001142470
NM_016487

NM_026411

RefSeq (protein)

NP_001135940
NP_001135942
NP_057571

NP_080687

Location (UCSC)Chr 6: 107.03 – 107.05 MbChr 10: 43.4 – 43.42 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Chromosome 6 open reading frame 203 is a protein that in humans is encoded by the C6orf203 gene. [5]

C6orf203 protein is reported to be localised to the mitochondria of eukaryotes and possess an evolutionarily conserved RNA-binding domain.[6][7]

One study propose C6orf203 to associate with mitochondrial RNA polymerase (POLRMT) and increase mitochondrial transcription to protect the cell from mitochondrial RNA loss during stress.[7] However, another study propose C6orf203 to associate with the mitoribosomal large subunit and regulate mitochondrial translation.[6]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000130349Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000019797Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Chromosome 6 open reading frame 203". Retrieved 2018-05-11.
  6. ^
    PMID 31396629
    .
  7. ^ .

Further reading