Collagen beta(1-o)galactosyltransferase 1
| COLGALT1 | |||
|---|---|---|---|
| Identifiers | |||
Gene ontology | |||
| Molecular function | |||
| Cellular component | |||
| Biological process | |||
| Sources:Amigo / QuickGO | |||
Ensembl | |||||||||
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| UniProt | |||||||||
| RefSeq (mRNA) | |||||||||
| RefSeq (protein) | |||||||||
| Location (UCSC) | Chr 19: 17.56 – 17.58 Mb | Chr 8: 72.06 – 72.08 Mb | |||||||
| PubMed search | [3] | [4] | |||||||
| View/Edit Human | View/Edit Mouse |
Collagen beta(1-O)galactosyltransferase 1 is a protein that in humans is encoded by the COLGALT1 gene. [5]
Function
The protein encoded by this gene is one of two enzymes that transfers galactose moieties to hydroxylysine residues of collagen and mannose binding lectin. This gene is constitutively expressed and encodes a soluble protein that localizes to the endoplasmic reticulum.
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000130309 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000034807 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: Collagen beta(1-O)galactosyltransferase 1". Retrieved 2017-05-16.
Further reading
- Schegg B, Hülsmeier AJ, Rutschmann C, Maag C, Hennet T (2009). "Core glycosylation of collagen is initiated by two beta(1-O)galactosyltransferases". Mol. Cell. Biol. 29 (4): 943–52. PMID 19075007.
- Liefhebber JM, Punt S, Spaan WJ, van Leeuwen HC (2010). "The human collagen beta(1-O)galactosyltransferase, GLT25D1, is a soluble endoplasmic reticulum localized protein". BMC Cell Biol. 11: 33. PMID 20470363.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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