Community Programs for Clinical Research on AIDS

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The Terry Beirn Community Programs for Clinical Research on AIDS (CPCRA) was a program sponsored by National Institutes of Health (NIH) in the United States.[1][2] Started in 1989, CPCRA was instrumental in some research databases being established. Research from the programs assisted the evaluation of therapies for treating HIV in diverse populations.[citation needed]

History

CPCRA was established in 1989[3] and included 15 research units. A Statistical Center at the University of Minnesota was funded from 1990 to 1997.[4][5]

CPCRA was one of four networks that NIH was using to conduct clinical trials that were looking to understand possible therapies for people with HIV infection.[6] Th CPCRA network was community-based with access to diverse populations across the spectrum of HIV diseases..."[7] The overall objective of the CPCRA is to design studies of sufficient size and duration of follow up to evaluate the long-term benefits and

unintended consequences of various treatment strategies using available agents to assess long-term immunologic, virology and clinical outcomes. CPCRA trials are designed with nested sub-studies aimed at understanding the pathogenesis of HIV infection and the public health implications of its treatment.[8]

By 2001, CPCRA had 4,244 people participating in their studies, with trials underway in 17 cities.[9]

The International Network for Strategic Initiatives in Global HIV Trials (INSIGHT) bio-repository system has its roots in the CPCRA.[10]

Research

An

highly active antiretroviral therapy-naïve, HIV-1-infected persons.[12]

References

  1. S2CID 8673486
    .
  2. PMID 9834882. Archived from the original
    (PDF) on 2016-04-27. Retrieved 2016-04-21.
  3. Assistant Secretary for Planning and Evaluation (ASPE). 7 January 2000. Archived from the original
    on 27 April 2016. Retrieved 21 April 2016.
  4. ^ Neaton, James. "Community Programs for Clinical Research on AIDS" – via grantome.com. {{cite journal}}: Cite journal requires |journal= (help)
  5. ^ "RDAtlas". Archived from the original on 2016-05-09. Retrieved 2016-04-21.
  6. ^ "NIAID Research on AIDS" (Press release). aidsinfo.nih.gov. 1 January 1995. Retrieved 22 April 2016.
  7. ^ "CPCRA - Community Programs for Clinical Research on AIDS". Archived from the original on 2013-02-01. Retrieved 2012-08-08.
  8. ^ "Community Programs for Clinical Research on AIDS (CPCRA)". Archived from the original on July 3, 2007. Retrieved April 17, 2007.
  9. ^ "HIV Infections in Minority Populations" (Press release). aidsinfo.nih.gov. 1 June 2002. Retrieved 22 April 2016.
  10. PMID 20978398
    .
  11. PMID 11915001
    .
  12. PMID 11306155
    .

External links
Scholia has a profile for Community Programs for Clinical Research on AIDS (Q5154845).


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