Coronary steal

Source: Wikipedia, the free encyclopedia.

Coronary steal (with its

circulation patterns leads to a reduction in the blood flow directed to the coronary circulation.[1] It is caused when there is narrowing of the coronary arteries and a coronary vasodilator[2]
is used – "stealing" blood away from those parts of the heart.

This happens as a result of the narrowed coronary arteries being always maximally dilated to compensate for the decreased upstream blood supply. Thus, dilating the resistance vessels in the coronary circulation causes blood to be shunted away from the coronary vessels supplying the ischemic zones, creating more ischemia.

Signs and symptoms

Mild coronary steal might not have any symptoms, but as the syndrome progresses, chest pain could usually be the first obvious symptom. In worse cases, symptoms can include dizziness, flushing, headaches, nausea and shortness of breath.[3]

Cause

It is associated with dipyridamole. Hence, dipyridamole is a pharmacological success diagnostically, but a therapeutic failure because of the coronary steal phenomenon.[4]

Coronary steal is also the mechanism in most drug-based cardiac stress tests; When a patient is incapable of doing physical activity they are given a vasodilator that produces a "cardiac steal syndrome" as a diagnostic procedure. The test result is positive if the patient's symptoms reappear or if ECG alterations are seen.[citation needed]

Hydralazine can potentially cause this condition as well, as it is a direct arteriolar vasodilator.[citation needed]

It has been associated with

nitroprusside.[5]

Other causes

Coronary arteriovenous fistula between coronary artery and another cardiac chamber, like, the coronary sinus, right atrium, or right ventricle may cause steal syndrome under conditions like myocardial infarction and possible angina or ventricular arrhythmias, if the shunt is large in magnitude.[6]

It can also be associated with new patterns of blood vessel growth.[7]

Diagnosis

Coronary steal syndrome can be diagnosed by: Electrocardiogram. Computed tomography angiogram. Coronary angiography. Stress testing with myocardial perfusion imaging[citation needed]

Treatment

It is sometimes treated by surgery.[8]

See also

References

  1. PMID 2787728
    .
  2. .
  3. .
  4. ^ Essentials of Medical Pharmacology, 5th Edition
  5. .
  6. ^ Harrisson's Principles of Internal Medicine, 17th Edition
  7. PMID 15958345
    .
  8. .