Beta-defensin 104 is a protein that in humans is encoded by the DEFB104Agene.[3]
Function
Chromosome 8p23 contains at least two copies of the duplicated beta-defensin cluster. This duplication results in two identical copies of defensin, beta 104, DEFB104A and DEFB104B, in head-to-head orientation. This gene, DEFB104A, represents the more centromeric copy.[3]
Patil AA, Cai Y, Sang Y, Blecha F, Zhang G (September 2005). "Cross-species analysis of the mammalian beta-defensin gene family: presence of syntenic gene clusters and preferential expression in the male reproductive tract". Physiological Genomics. 23 (1): 5–17.
Vankeerberghen A, Scudiero O, De Boeck K, Macek M, Pignatti PF, Van Hul N, Nuytten H, Salvatore F, Castaldo G, Zemkova D, Vavrova V, Cassiman JJ, Cuppens H (May 2005). "Distribution of human beta-defensin polymorphisms in various control and cystic fibrosis populations". Genomics. 85 (5): 574–81.
Boniotto M, Ventura M, Eskdale J, Crovella S, Gallagher G (2005). "Evidence for duplication of the human defensin gene DEFB4 in chromosomal region 8p22-23 and implications for the analysis of SNP allele distribution". Genetic Testing. 8 (3): 325–7.