Dishevelled binding antagonist of beta catenin 2
DACT2 | |||
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Identifiers | |||
Gene ontology | |||
Molecular function | |||
Cellular component | |||
Biological process | |||
Sources:Amigo / QuickGO |
Ensembl | |||||||||
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UniProt | |||||||||
RefSeq (mRNA) | |||||||||
RefSeq (protein) | |||||||||
Location (UCSC) | Chr 6: 168.29 – 168.32 Mb | Chr 17: 14.42 – 14.42 Mb | |||||||
PubMed search | [3] | [4] |
View/Edit Human | View/Edit Mouse |
Dishevelled binding antagonist of beta catenin 2 is a protein that in humans is encoded by the DACT2 gene. [5]
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000164488 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000048826 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: Dishevelled binding antagonist of beta catenin 2". Retrieved 2017-09-10.
Further reading
- Koga Y, Yao T, Hirahashi M, Kumashiro Y, Ohji Y, Yamada T, Tanaka M, Tsuneyoshi M (2008). "Flat adenoma-carcinoma sequence with high-malignancy potential as demonstrated by CD10 and beta-catenin expression: a different pathway from the polypoid adenoma-carcinoma sequence". Histopathology. 52 (5): 569–77. S2CID 26122361.
- Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR (2010). "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score". Mol. Med. 16 (7–8): 247–53. PMID 20379614.
- Hendrickson SL, Lautenberger JA, Chinn LW, Malasky M, Sezgin E, Kingsley LA, Goedert JJ, Kirk GD, Gomperts ED, Buchbinder SP, Troyer JL, O'Brien SJ (2010). "Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression". PLOS ONE. 5 (9): e12862. PMID 20877624.
- Jia Y, Yang Y, Brock MV, Zhan Q, PMID 22806826.
- Cheng H, Lu M, Mao LJ, Wang JQ, Li W, Wen RM, Chen JC (2012). "Relationships among MTHFR a1298c gene polymorphisms and methylation status of Dact1 gene in transitional cell carcinomas". Asian Pac. J. Cancer Prev. 13 (10): 5069–74. PMID 23244112.
- Zhang X, Yang Y, Liu X, Herman JG, Brock MV, Licchesi JD, Yue W, Pei X, Guo M (2013). "Epigenetic regulation of the Wnt signaling inhibitor DACT2 in human hepatocellular carcinoma". Epigenetics. 8 (4): 373–82. PMID 23449122.
- Gao S, Yang Z, Zheng ZY, Yao J, Zhang F, Wu LM, Xie HY, Zhou L, Zheng SS (2013). "Reduced expression of DACT2 promotes hepatocellular carcinoma progression: involvement of methylation-mediated gene silencing". World J Surg Oncol. 11: 57. PMID 23496880.
- Hou J, Liao LD, Xie YM, Zeng FM, Ji X, Chen B, Li LY, Zhu MX, Yang CX, Qing-Zhao, Chen T, Xu XE, Shen J, Guo MZ, Li EM, Xu LY (2013). "DACT2 is a candidate tumor suppressor and prognostic marker in esophageal squamous cell carcinoma". Cancer Prev Res (Phila). 6 (8): 791–800. PMID 23803417.
- Wang S, Dong Y, Zhang Y, Wang X, Xu L, Yang S, Li X, Dong H, Xu L, Su L, Ng SS, Chang Z, Sung JJ, Zhang X, Yu J (2015). "DACT2 is a functional tumor suppressor through inhibiting Wnt/β-catenin pathway and associated with poor survival in colon cancer". Oncogene. 34 (20): 2575–85. PMID 25023701.