Dumfriesshire, Clydesdale and Tweeddale (UK Parliament constituency)

Dumfriesshire, Clydesdale and Tweeddale is a

• The Dumfries and Galloway Council wards of Annandale East and Eskdale, Annandale North, Annandale South, Mid and Upper Nithsdale (most), Lochar (small part), and Nith (small part);
• The Scottish Borders Council wards of Tweeddale East and Tweeddale West (most); and
• The South Lanarkshire Council wards of Clydesdale East (majority) and Clydesdale South (minority).

2024–present: Further to the 2023 review of Westminster constituencies which came into effect for the 2024 general election, the constituency was subject to minor boundary changes, losing the part of the Nith ward, offset by the gain of a further part of the Lochar ward. The remainder of the Clydesdale East ward was also added.^[4][5]

One of the largest seats in terms of area, the constituency is predominantly rural and is very sparsely populated. It stretches from 10 miles outside of Edinburgh in the northeast all the way down to Gretna at the border with England. It is also the only seat in Scotland that has been held by the Conservatives in every election since its creation. It contains some very affluent areas as well as some more working-class areas; however, it is a large rural seat where farming is a big source of employment. The M74, which is the main road between Scotland and England, runs through the constituency as do the West Coast Mainline and Glasgow South Western railway lines. Its largest towns are

Clydesdale had been a safe Labour seat since the 1980s, and Tweeddale, Ettrick and Lauderdale had been a Liberal/Liberal Democrat seat since 1983.

Following the boundary review for the 2005 general election, Labour held a clear majority of 12% over the Conservatives, according to calculations of notional results (an estimate of how the seat would have voted if it had existed at the previous election) and the seat was 96th

In 2010, Mundell was re-elected, with an increased majority. In 2015, after the SNP landslide victory in Scotland, he narrowly defeated the SNP candidate, Emma Harper by 798 votes, and was the only Scottish Conservative MP elected.[9] However, following the SNP's losses at the 2017 snap general election, the Conservatives gained 12 seats in Scotland, with Mundell increasing his majority to 9,441 votes. Mundell was re-elected at the 2019 general election, but with a reduced majority of 3,781 votes, in an election where the SNP made gains across Scotland at the expense of Labour and the Conservatives. Although his vote share fell considerably, Mundell was re-elected at the 2024 election with a slightly increased majority of 4,242 votes, as the SNP vote fell even further, with Labour coming in a close third.