EDEM1
| EDEM1 | |||
|---|---|---|---|
| Identifiers | |||
Gene ontology | |||
| Molecular function | |||
| Cellular component | |||
| Biological process |
| ||
| Sources:Amigo / QuickGO | |||
Ensembl | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| UniProt | |||||||||
| RefSeq (mRNA) | |||||||||
| RefSeq (protein) | |||||||||
| Location (UCSC) | Chr 3: 5.19 – 5.22 Mb | Chr 6: 108.81 – 108.84 Mb | |||||||
| PubMed search | [3] | [4] | |||||||
| View/Edit Human | View/Edit Mouse |
ER degradation-enhancing alpha-mannosidase-like 1 is an enzyme that in humans is encoded by the EDEM1 gene.[5][6]
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000134109 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000030104 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- S2CID 24092303.
- ^ "Entrez Gene: EDEM1 ER degradation enhancer, mannosidase alpha-like 1".
Further reading
- Nagase T, Seki N, Ishikawa K, et al. (1997). "Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain". DNA Res. 3 (5): 321–9, 341–54. PMID 9039502.
- Hosokawa N, Wada I, Hasegawa K, et al. (2001). "A novel ER alpha-mannosidase-like protein accelerates ER-associated degradation". EMBO Rep. 2 (5): 415–22. PMID 11375934.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. PMID 12477932.
- Oda Y, Hosokawa N, Wada I, Nagata K (2003). "EDEM as an acceptor of terminally misfolded glycoproteins released from calnexin". Science. 299 (5611): 1394–7. S2CID 28716209.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. PMID 15489334.
- Olivari S, Galli C, Alanen H, et al. (2005). "A novel stress-induced EDEM variant regulating endoplasmic reticulum-associated glycoprotein degradation". J. Biol. Chem. 280 (4): 2424–8. PMID 15579471.
- Oda Y, Okada T, Yoshida H, et al. (2006). "Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation". J. Cell Biol. 172 (3): 383–93. PMID 16449189.
- Hosokawa N, Wada I, Natsuka Y, Nagata K (2006). "EDEM accelerates ERAD by preventing aberrant dimer formation of misfolded alpha1-antitrypsin". Genes Cells. 11 (5): 465–76. S2CID 19832510.
- Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. PMID 17353931.
- Zuber C, Cormier JH, Guhl B, et al. (2007). "EDEM1 reveals a quality control vesicular transport pathway out of the endoplasmic reticulum not involving the COPII exit sites". Proc. Natl. Acad. Sci. U.S.A. 104 (11): 4407–12. PMID 17360537.
 | This article on a gene on human chromosome 3 is a stub. You can help Wikipedia by expanding it. |