Exosome component 1

Source: Wikipedia, the free encyclopedia.
EXOSC1
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo / QuickGO
Ensembl
UniProt
RefSeq (mRNA)

NM_001164561
NM_025644
NM_001320231
NM_001320232
NM_001320233

RefSeq (protein)

NP_001158033
NP_001307160
NP_001307161
NP_001307162
NP_079920

Location (UCSC)Chr 10: 97.44 – 97.45 MbChr 19: 41.91 – 41.92 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

3'-5' exoribonuclease CSL4 homolog is an enzyme that in humans is encoded by the EXOSC1 gene.[5][6][7]

This gene encodes a core component of the exosome complex. The mammalian exosome is required for rapid degradation of AU rich element-containing RNAs but not for poly(A) shortening. The association of this protein with the exosome is mediated by protein-protein interactions with ribosomal RNA-processing protein 42 and ribosomal RNA-processing protein 46.[7]

Interactions

Exosome component 1 has been shown to

interact
with:

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000171311Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000034321Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^
    PMID 11812149
    .
  6. .
  7. ^ a b "Entrez Gene: EXOSC1 exosome component 1".
  8. ^
    PMID 12419256
    .

Further reading