FIZ1
FIZ1 | |||
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Identifiers | |||
Gene ontology | |||
Molecular function | |||
Cellular component | |||
Biological process | |||
Sources:Amigo / QuickGO |
Ensembl | |||||||||
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UniProt | |||||||||
RefSeq (mRNA) |
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RefSeq (protein) |
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Location (UCSC) | Chr 19: 55.59 – 55.6 Mb | Chr 7: 5.01 – 5.02 Mb | |||||||
PubMed search | [3] | [4] |
View/Edit Human | View/Edit Mouse |
FLT3 interacting zinc finger 1 is a protein that in humans is encoded by the FIZ1 gene. [5]
Function
This gene encodes zinc finger protein, which interacts with a receptor tyrosine kinase involved in the regulation of hematopoietic and lymphoid cells. This gene product also interacts with a transcription factor that regulates the expression of rod-specific genes in retina. [provided by RefSeq, Jul 2008].
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000179943 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000061374 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: FLT3 interacting zinc finger 1". Retrieved 2018-05-22.
Further reading
- Mitton KP, Swain PK, Khanna H, Dowd M, Apel IJ, Swaroop A (February 2003). "Interaction of retinal bZIP transcription factor NRL with Flt3-interacting zinc-finger protein Fiz1: possible role of Fiz1 as a transcriptional repressor". Hum. Mol. Genet. 12 (4): 365–73. PMID 12566383.
- Mali RS, Zhang X, Hoerauf W, Doyle D, Devitt J, Loffreda-Wren J, Mitton KP (February 2007). "FIZ1 is expressed during photoreceptor maturation, and synergizes with NRL and CRX at rod-specific promoters in vitro". Exp. Eye Res. 84 (2): 349–60. PMID 17141759.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.