FMNL3
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Formin-like protein 3 (FMNL3), also known as WW domain-binding protein 3 (WBP-3), is a protein that in humans is encoded by the FMNL3 gene.[5][6]
Function
The protein encoded by this gene contains a
isoforms have been described.[5] The C-terminus has been shown to accelerate actin polymerization activity of this protein through its WH2-like motif.[7] FMNL3 has been crystallized in complex with actin providing insight into the mechanism of formin-mediated actin nucleation.[8]
See also
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000161791 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000023008 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ a b "Entrez Gene: formin-like 3".
- PMID 12684686.
- PMID 22094460.
- PMID 23222643.
Further reading
- Bedford MT, Chan DC, Leder P (May 1997). "FBP WW domains and the Abl SH3 domain bind to a specific class of proline-rich ligands". The EMBO Journal. 16 (9): 2376–83. PMID 9171351.
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