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English: The 35S RNA is particularly complex, containing a highly structured 600 nucleotide long leader sequence with six to eight short open reading frames (ORFs) (Fütterer et al., 1988; Pooggin et al., 1998). This leader is followed by seven tightly arranged longer ORFs that encode all the viral proteins (reviewed by Hohn and Fütterer, 1997). The mechanism of expression of these proteins is very special. The ORF VI protein (encoded by the 19S RNA) controls translation reinitiation of major open reading frames on the polycistronic 35S RNA. TAV function depends on its association with polysomes and eukaryotic initiation factor eIF3 (Park et al., 2001).
  • ORF1 – Movement Protein (MP P03545)
  • ORF2 – Aphid/Insect Transmission Factor (ATF, P03548)
  • ORF3 – Virion-associated protein (VAP, P03551).
  • ORF4 – Capsid Protein (CP, P03542)
  • ORF5 – pro-pol (P03554): Protease, bifunctional Reverse Transcriptase and RNaseH
  • ORF6 – Transactivator/viroplasmin (TAV, P03559)
  • ORF7 – Unknown (dispensable?)
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  • attribution – You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
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17 February 2005

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current02:49, 7 February 2005Thumbnail for version as of 02:49, 7 February 2005857 × 815 (32 KB)Zeimusu{{GFDL}} {{cc-by-sa}} The 35S RNA is particularly complex, containing a highly structured 600 nucleotide long leader sequence with six to eight short open reading frames (ORFs) (Fütterer et al., 1988; Pooggin et al., 1998). This leader is followed by sev
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