Genomics England
Formation | 5 July 2013 |
---|---|
Headquarters | One Canada Square, Canary Wharf, London, England[1] |
Parent organization | Department of Health and Social Care |
Website | www |
Genomics England is a British company set up and owned by the United Kingdom
In the summer of 2019, Chris Wigley was appointed CEO of Genomics England, starting in October 2019.[6] Wigley is a former McKinsey executive known for applying machine learning and artificial intelligence technology.[7]
Activity
Genomics England was formally established as a company on 17 April 2013[8] and was formally launched on 5 July 2013 as part of the celebrations for the 65th Birthday of the UK's National Health Service[9] In August 2014, the
The UK Government also committed £250 million to genomics in the 2015 Spending Review, which ensures the continued role of Genomics England to deliver the project, beyond the life of the project and up to 2021.[11]
On March 26, 2015, AstraZeneca announced that it joined a public-private consortium with Genomics England to accelerate the development of new diagnostics and treatments arising from the 100,000 Genomes Project.[12]
In October 2018, the U.K.'s
In July 2019, Genomics England announced Data Release 7, which included the 100,000th whole genome available to researchers.[14]
In June 2020, Genomics England announced a partnership with UK-based biotechnology company Lifebit to deploy a genomic research platform aimed at utilizing the genomic data generated through the 100,000 Genomes Project.[15]
In 2021 it developed a vision regarding newborn screening, initiating a research study called Generation Study looking for 200 rare conditions in parallel to the standard NHS newborn screen for 9 rare, serious and treatable health conditions.[16]
Board members
The Board of Genomics England includes a number of notable scientists:[17]
- Sir John Chisholm (Executive Chair), former chair of the UK Medical Research Council
- Sir Mark Caulfield (Chief Scientist),[4] Queen Mary University of London
- Sir John Bell, University of Oxford
- Dame Chief Medical Officer (United Kingdom)
- Ewan Birney (Non-executive Director), Director of the European Bioinformatics Institute (EMBL-EBI)[18]
- Sir Malcolm Grant (Non-executive Director), Chair of the NHS England Board
- Michael Parker (Non-executive Director; Chair of the Ethics Advisory Committee), University of Oxford
- Jon Symonds (Non-executive Director), Chair of Innocoll AG, former Chief Financial Officer of Novartis AG
- Dame Kay Davies (Non-executive Director), University of Oxford
Baroness Nicola Blackwood of North Oxford became Chair of Genomics England in May 2020.[19]
History
Genomics England was established in July 2013 as a company fully owned by the
A 2019 review identified the 100,000 Genomes Project as an exemplar in involving the public in genomic research.[22] In addition to the delivery of the 100,000 Genomes Project, it is hoped that Genomics England will also mark the beginnings of a UK genomics industry and the start of a personalised medicine service for the NHS.[20]
NHS Genomic Medicine Centres
Following the pilot studies for the
- East of England NHS GMC – designated for both cancer and rare disease. Led by Cambridge University Hospitals NHS Foundation Trust
- South London NHS GMC – designated for both cancer and rare disease. Led by Guy's and St Thomas' NHS Foundation Trust
- North West Coast NHS GMC – designated for both cancer and rare disease. Led by Liverpool Women's NHS Foundation Trust
- Greater Manchester NHS GMC – designated for both cancer and rare disease. Led by Central Manchester University Hospitals NHS Foundation Trust
- North Thames NHS GMC – designated for both cancer and rare disease. Led by Great Ormond Street Hospital for Children NHS Foundation Trust
- North East and North Cumbria NHS GMC – designated GMC for rare disease only. Led by The Newcastle upon Tyne Hospitals NHS Foundation Trust
- Oxford NHS GMC – designated for both cancer and rare disease. Led by Oxford University Hospitals NHS Trust
- South West Peninsula NHS GMC – designated for both cancer and rare disease. Led by Royal Devon and Exeter NHS Foundation Trust
- Wessex NHS GMC – designated for both cancer and rare disease. Led by University Hospital Southampton NHS Foundation Trust
- Imperial College Health Partners NHS GMC – designated for both cancer and rare disease. Led by Imperial College Healthcare NHS Trust
- West Midlands NHS GMC – designated for both cancer and rare disease. Led by University Hospitals Birmingham NHS Foundation Trust
In December 2015, two new NHS Genomic Medicine Centres were announced by NHS England:[24]
- Yorkshire and Humber NHS GMC – designated for both cancer and rare disease.
- West of England NHS GMC – designated for both cancer and rare disease.
There are now 13 designated NHS Genomic Medicine Centres (GMCs) across the country.
See also
References
- ^ "Contact us". Genomics England. Retrieved 25 November 2023.
- PMID 26871914.
- S2CID 33053129.
- ^ PMID 26536223.
- PMID 26310768.
- ^ "Genomics England Appoints AI Specialist Chris Wigley as CEO". 27 July 2019.
- ^ "Chris Wigley appointed CEO of Genomics England | Genomics England". 26 July 2019.
- ^ "GENOMICS ENGLAND LIMITED". Companies House. Retrieved 3 December 2017.
- Department of Health (England). 5 July 2013. Retrieved 3 December 2017.
- ^ Gallagher, James (1 August 2014). "DNA project 'to make UK world genetic research leader'". BBC News. Retrieved 1 August 2014.
- ^ "Cancer patients join genome sequencing project - News stories - GOV.UK". www.gov.uk. Retrieved 6 June 2016.
- ^ "AstraZeneca joins Genomics England consortium". 26 March 2015. Retrieved 31 January 2023.
- ^ "Secretary of State for Health and Social Care announces ambition to sequence 5 million genomes within five years | Genomics England". 2 October 2018.
- ^ "Over 100,000 whole genome sequences now available for approved researchers | Genomics England". 31 July 2019.
- ^ "Genomics England launches next-generation research platform central to UK COVID-19 response". 29 June 2020.
- ^ "Newborn Genomes Programme". Genomics England. nd. Retrieved 20 March 2024.
- ^ "The Board - Genomics England". genomicsengland.co.uk. July 2013. Retrieved 12 September 2014.
- ^ "Professor Ewan Birney appointed to the Genomics England Board | Genomics England". Genomics England. 26 May 2016. Retrieved 6 June 2016.
- ^ "Register of Interests for Baroness Blackwood of North Oxford - MPs and Lords - UK Parliament". members.parliament.uk. Retrieved 26 February 2021.
- ^ a b Ramesh, Randeep (4 July 2013). "Jeremy Hunt launches genomics body to oversee healthcare revolution". The Guardian. Retrieved 12 September 2014.
- ^ a b "DNA mapping to better understand cancer, rare diseases and infectious diseases". UK Government. 5 July 2013. Retrieved 26 May 2016.
- PMID 31024880.
- ^ "Genomics England - How we work". Genomics England Limited. Retrieved 3 April 2021.
- ^ "NHS England » New NHS centres add their might to world-leading genomics project". www.england.nhs.uk. Retrieved 17 December 2015.