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HLA-B (alpha)-β2MG with bound peptide
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major histocompatibility complex (human), class I, B70
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Alleles
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*1503, *1509, *1510, *1518, *1529, *1537
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Structure (See HLA-B)
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Shared data
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Locus
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HLA-B70 (B70) is an HLA-B serotype. The serotype identifies certain B*15 gene-allele protein products of HLA-B.[1]
B70 is one of many split antigens of the broad antigen, B15.
Serotype
Serotypes B15, B62, B63, B70, B71, B72, B75, B76, B77 recognition of the
HLA B*15 gene products[2]
B*15 |
B15
|
B62 |
B63
|
B70 |
B71 |
B72
|
B75 |
B76 |
B77 |
Sample
|
allele |
% |
% |
% |
% |
% |
% |
% |
% |
% |
size (N)
|
*1503 |
1 |
|
|
61 |
|
10 |
|
|
|
2569
|
*1509 |
|
|
|
53 |
|
|
|
|
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65
|
*1510 |
1 |
|
|
49 |
2 |
2 |
1 |
|
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1204
|
*1518 |
|
|
|
51 |
3 |
|
|
|
|
552
|
*1529 |
|
|
|
19 |
|
|
|
|
|
21
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*1537 |
|
|
|
30 |
|
|
|
|
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34
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Alleles link-out to IMGT/HLA Databease at EBI
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Alleles
HLA B*1503 frequencies
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|
freq
|
ref. |
Population |
(%)
|
[3] |
Burkina Faso Rimaibe |
13.8
|
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Guinea Bissau |
10.8
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Cameroon Pygmy Baka |
10.0
|
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South African Natal Zulu |
9.5
|
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Kenya Luo |
8.9
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Ivory Coast Akan Adiopodoume |
8.0
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Kenya Nandi |
7.9
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Cameroon Sawa |
7.7
|
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Zimbabwe Harare Shona |
7.7
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USA African America |
7.3
|
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Burkina Faso Fulani |
7.1
|
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Mali Bandiagara |
6.9
|
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Senegal Niokholo Mandenka |
6.9
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Cape Verde SE Islands |
6.5
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Kenya |
6.3
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Uganda Kampala |
6.2
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Sudanese |
6.0
|
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Zambia Lusaka |
5.7
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Cameroon Yaounde |
4.9
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Cape Verde NW Islands |
4.8
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Oman |
4.7
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Cameroon Bamileke |
4.5
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Tunisia Tunis |
4.5
|
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Cameroon Beti |
3.7
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Brazil Belo Horizonte |
3.2
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Azores Terceira Island |
2.4
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Madeira |
2.2
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Saudi Arabia Guraiat and Hail |
2.0
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Tunisia |
2.0
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United Arab Emerates |
1.5
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Brazil |
1.4
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Cuban White |
1.4
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Morocco Nador Metalsa |
1.4
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Mexico Mestizos |
1.2
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Italy Bergamo |
1.1
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Portugal North |
1.1
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American Samoa |
1.0
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Iran Baloch |
1.0
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Mexico Guadalajara Mestizos (2) |
1.0
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Azores Central Islands |
0.9
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Israel Ashk. and Non-Ashk. Jews |
0.9
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Taiwan Hakka |
0.9
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Croatia |
0.7
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HLA B*1509 frequencies
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|
freq
|
ref. |
Population |
(%)
|
[3] |
Burkina Faso Fulani |
4.1
|
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India West Coast Parsis |
3.0
|
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Spain Eastern Andalusia Gipsy |
3.0
|
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Mexico Mestizos |
2.4
|
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Italy South Campania |
1.2
|
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Burkina Faso Rimaibe |
1.1
|
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China Inner Mongolia |
1.0
|
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Mali Bandiagara |
0.7
|
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Czech Republic |
0.5
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HLA B*1510 frequencies
|
|
freq
|
ref. |
Population |
(%)
|
[3] |
South African Natal Zulu |
8.5
|
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Zimbabwe Harare Shona |
8.4
|
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Ivory Coast Akan Adiopodoume |
5.7
|
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Kenya |
5.2
|
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Zambia Lusaka |
4.6
|
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Cameroon Sawa |
3.8
|
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Guinea Bissau |
3.8
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Kenya Luo |
3.6
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Senegal Niokholo Mandenka |
3.2
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Cameroon Beti |
2.8
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USA African Americans (3) |
2.7
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Uganda Kampala |
2.5
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Mexico Mestizos |
2.4
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Mali Bandiagara |
2.2
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Kenya Nandi |
1.7
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Brazil Belo Horizonte |
1.6
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Cameroon Bamileke |
1.3
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Cuban Mulatto |
1.2
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Cameroon Yaounde |
1.1
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Iran Baloch |
1.0
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Sudanese |
1.0
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Tunisia |
1.0
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Brazil Terena |
0.9
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Cape Verde NW Islands |
0.8
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United Arab Emerates |
0.8
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USA North American Natives |
0.8
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Guadalajara Mestizos (2) |
0.5
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HLA B*1518 frequencies
|
|
freq
|
ref. |
Population |
(%)
|
[3] |
South Africa Natal Tamil |
4.1
|
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Autonomous Tibetans |
3.8
|
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India Mumbai Marathas |
3.7
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China North Han |
2.9
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USA Hawaii Okinawa |
2.9
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China Guangzhou Han |
2.4
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India Andhra Pradesh Golla |
2.4
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China Beijing |
2.3
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Taiwan Hakka |
1.8
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Japan |
1.7
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India North Delhi |
1.6
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China Inner Mongolia |
1.5
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China Qinghai Hui |
1.4
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Czech Republic |
1.4
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China Yunnan Nu |
1.3
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Shijiazhuang Tianjian Han |
1.1
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Ivory Coast Akan Adiopodoume |
1.1
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Senegal Niokholo Mandenka |
1.1
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Zambia Lusaka |
1.1
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Portugal Centre |
1.0
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Singapore Javanese Indonesians |
1.0
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Thailand (3) |
1.0
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South Korea (3) |
0.9
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Cape Verde Islands |
0.8
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France South East |
0.8
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Guinea Bissau |
0.8
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China South Han |
0.7
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China Yunnan Lisu |
0.7
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Russia Tuva (2) |
0.6
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Singapore Chinese Han |
0.6
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Spain Eastern Andalusia |
0.6
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References