HSPB2
| HSPB2 | |||
|---|---|---|---|
| Identifiers | |||
Gene ontology | |||
| Molecular function | |||
| Cellular component | |||
| Biological process | |||
| Sources:Amigo / QuickGO | |||
Ensembl | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| UniProt | |||||||||
| RefSeq (mRNA) | |||||||||
| RefSeq (protein) | |||||||||
| Location (UCSC) | Chr 11: 111.91 – 111.91 Mb | Chr 9: 50.66 – 50.66 Mb | |||||||
| PubMed search | [3] | [4] | |||||||
| View/Edit Human | View/Edit Mouse |
Heat shock protein beta-2 is a protein that in humans is encoded by the HSPB2 gene.[5][6][7]
Interactions
HSPB2 has been shown to
interact
with:
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000170276 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000038086 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- PMID 9344664.
- ^ PMID 9490724.
- ^ "Entrez Gene: HSPB2 heat shock 27kDa protein 2".
- ^ PMID 10625651.
- PMID 14594798.
- PMID 11342557.
- PMID 18950704.
Further reading
- Concannon CG, Gorman AM, Samali A (2003). "On the role of Hsp27 in regulating apoptosis". Apoptosis. 8 (1): 61–70. S2CID 18464958.
- Elisei R, Weightman D, Kendall-Taylor P, Vassart G, Ludgate M (1993). "Muscle autoantigens in thyroid associated ophthalmopathy: the limits of molecular genetics". J. Endocrinol. Invest. 16 (7): 533–40. S2CID 23857370.
- Deak M, Clifton AD, Lucocq LM, Alessi DR (1998). "Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB". EMBO J. 17 (15): 4426–41. PMID 9687510.
- Sugiyama Y, Suzuki A, Kishikawa M, Akutsu R, Hirose T, Waye MM, Tsui SK, Yoshida S, Ohno S (2000). "Muscle develops a specific form of small heat shock protein complex composed of MKBP/HSPB2 and HSPB3 during myogenic differentiation". J. Biol. Chem. 275 (2): 1095–104. PMID 10625651.
- Baysal BE, Willett-Brozick JE, Taschner PE, Dauwerse JG, Devilee P, Devlin B (2001). "A high-resolution integrated map spanning the SDHD gene at 11q23: a 1.1-Mb BAC contig, a partial transcript map and 15 new repeat polymorphisms in a tumour-suppressor region". Eur. J. Hum. Genet. 9 (2): 121–9. PMID 11313745.
- Nakagawa M, Tsujimoto N, Nakagawa H, Iwaki T, Fukumaki Y, Iwaki A (2001). "Association of HSPB2, a member of the small heat shock protein family, with mitochondria". Exp. Cell Res. 271 (1): 161–8. PMID 11697892.
- Ito H, Kamei K, Iwamoto I, Inaguma Y, García-Mata R, Sztul E, Kato K (2002). "Inhibition of proteasomes induces accumulation, phosphorylation, and recruitment of HSP27 and alphaB-crystallin to aggresomes". J. Biochem. 131 (4): 593–603. PMID 11926998.
- Boxman IL, Kempenaar J, de Haas E, Ponec M (2003). "Induction of HSP27 nuclear immunoreactivity during stress is modulated by vitamin C.". Exp. Dermatol. 11 (6): 509–17. S2CID 25384331.
- Patel VM, Heinel LA, Provencio JJ, Vinall PE, Kramer MS, Rosenwasser RH (2003). "Validation of image analysis for enzyme histochemical and immunocytochemical staining". Biotechnic & Histochemistry. 77 (4): 213–21. PMID 12503731.
- Mao H, Li F, Ruchalski K, Mosser DD, Schwartz JH, Wang Y, Borkan SC (2003). "hsp72 inhibits focal adhesion kinase degradation in ATP-depleted renal epithelial cells". J. Biol. Chem. 278 (20): 18214–20. PMID 12611892.
- Yonekura N, Yokota S, Yonekura K, Dehari H, Arata S, Kohama G, Fujii N (2003). "Interferon-gamma downregulates Hsp27 expression and suppresses the negative regulation of cell death in oral squamous cell carcinoma lines". Cell Death Differ. 10 (3): 313–22. PMID 12700631.
- Kantham L, Kerr-Bayles L, Godde N, Quick M, Webb R, Sunderland T, Bond J, Walder K, Augert G, Collier G (2003). "Beacon interacts with cdc2/cdc28-like kinases". Biochem. Biophys. Res. Commun. 304 (1): 125–9. PMID 12705895.
- Yaglom J, O'Callaghan-Sunol C, Gabai V, Sherman MY (2003). "Inactivation of dual-specificity phosphatases is involved in the regulation of extracellular signal-regulated kinases by heat shock and hsp72". Mol. Cell. Biol. 23 (11): 3813–24. PMID 12748284.
- Park KJ, PMID 12829720.
- Wen FC, Li YH, Tsai HF, Lin CH, Li C, Liu CS, Lii CK, Nukina N, Hsieh M (2003). "Down-regulation of heat shock protein 27 in neuronal cells and non-neuronal cells expressing mutant ataxin-3". FEBS Lett. 546 (2–3): 307–14. S2CID 35025906.
- Parcellier A, Schmitt E, Gurbuxani S, Seigneurin-Berny D, Pance A, Chantôme A, Plenchette S, Khochbin S, Solary E, Garrido C (2003). "HSP27 is a ubiquitin-binding protein involved in I-kappaBalpha proteasomal degradation". Mol. Cell. Biol. 23 (16): 5790–802. PMID 12897149.
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