Harlequin color change

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Harlequin color change is a

newborn babies characterized by momentary red color changes of half the child, sharply demarcated at the body's midline. This transient change occurs in approximately 10% of healthy newborns.[1] It is seen usually between two and five days of birth. The condition lasts from 30 seconds to 20 minutes and then fades. It may recur when the infant is placed on their side, as the intensity of color has been shown to be gravity dependent and considerably variable from one infant to another.[2]

The dark red color skin of the newborn with harlequin signs indicates

intracranial injury, meningitis and anesthesia have been mentioned in the literature.[4][5][6][7][8][9] Probable differential diagnosis are Port-wine stain and nascent hemangioma of infancy, but these can be differentiated due to transient nature of this condition.[1]

Hypothesized pathogenesis involves temporary imbalance in the tone of cutaneous blood vessels secondary to hypothalamic immaturity.[10]

This condition was first described by Neligan and Strang in 1952 and was named so.[5]

References

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  2. ^ M.A. Selimoglu et al., "PICTURE OF THE MONTH - HARLEQUIN COLOR-CHANGE", Archives of Pediatrics & Adolescent Medicine, 149(10), 1995, pp. 1171-1172
  3. ^ {Perry, S. E., Hockenberry, M. J., Lowdermilk, D. L., & Wilson, D. (n.d.). Maternal child nursing care.}
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See also

  • List of cutaneous conditions