IFNA8

IFNA8
Identifiers
Gene ontology
Molecular function	cytokine activity; type I interferon receptor binding; cytokine receptor binding;
Cellular component	extracellular region; extracellular space;
Biological process	natural killer cell activation involved in immune response; B cell differentiation; defense response; B cell proliferation; blood coagulation; positive regulation of peptidyl-serine phosphorylation of STAT protein; humoral immune response; adaptive immune response; defense response to virus; type I interferon signaling pathway; response to exogenous dsRNA; T cell activation involved in immune response; innate immune response; cytokine-mediated signaling pathway; regulation of signaling receptor activity;
	Sources:Amigo / QuickGO

Ensembl


ENSG00000120242


n/a

UniProt


P32881


n/a

RefSeq (mRNA)


NM_002170


n/a

RefSeq (protein)


NP_002161


n/a

Location (UCSC)

Chr 9: 21.41 – 21.41 Mb

n/a

PubMed search

^[2]

n/a

Wikidata

View/Edit Human

Interferon alpha-8 is a protein that in humans is encoded by the IFNA8 gene.^[3]^[4]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000120242 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
PMID 1385305
.

^ "Entrez Gene: IFNA8 interferon, alpha 8".

Further reading

Henco K, Brosius J, Fujisawa A, et al. (1985). "Structural relationship of human interferon alpha genes and pseudogenes". J. Mol. Biol. 185 (2): 227–60.
PMID 4057246
.

Goeddel DV, Leung DW, Dull TJ, et al. (1981). "The structure of eight distinct cloned human leukocyte interferon cDNAs". Nature. 290 (5801): 20–6.
S2CID 1900300
.

Yelverton E, Leung D, Weck P, et al. (1981). "Bacterial synthesis of a novel human leukocyte interferon". Nucleic Acids Res. 9 (3): 731–41.
PMID 6164048
.

Bowden DW, Mao J, Gill T, et al. (1984). "Cloning of eukaryotic genes in single-strand phage vectors: the human interferon genes". Gene. 27 (1): 87–99.
PMID 6325303
.

Tiefenbrun N, Melamed D, Levy N, et al. (1996). "Alpha interferon suppresses the cyclin D3 and cdc25A genes, leading to a reversible G0-like arrest". Mol. Cell. Biol. 16 (7): 3934–44.
PMID 8668211
.

Hussain M, Gill DS, Liao MJ, Testa D (1997). "Interferon-alpha 8b is the only variant of interferon-alpha 8 identified in a large human population". J. Interferon Cytokine Res. 16 (7): 523–9.
PMID 8836918
.

Nyman TA, Tölö H, Parkkinen J, Kalkkinen N (1998). "Identification of nine interferon-alpha subtypes produced by Sendai virus-induced human peripheral blood leucocytes". Biochem. J. 329. ( Pt 2) (2): 295–302.
PMID 9425112
.

Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903.
PMID 12477932
.

Hardy MP, Owczarek CM, Jermiin LS, et al. (2005). "Characterization of the type I interferon locus and identification of novel genes". Genomics. 84 (2): 331–45.
PMID 15233997
.

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Retrieved from "https://en.wikipedia.org/w/index.php?title=IFNA8&oldid=1115889343"

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000120242 – Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid1385305-3] PMID 1385305
.

[entrez-4] "Entrez Gene: IFNA8 interferon, alpha 8".

[2]

[3]

[4]