IPO7
| IPO7 | |||
|---|---|---|---|
| Identifiers | |||
Gene ontology | |||
| Molecular function | |||
| Cellular component | |||
| Biological process | |||
| Sources:Amigo / QuickGO | |||
Ensembl | |||||||||
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| UniProt | |||||||||
| RefSeq (mRNA) | |||||||||
| RefSeq (protein) | |||||||||
| Location (UCSC) | Chr 11: 9.38 – 9.45 Mb | Chr 7: 109.62 – 109.66 Mb | |||||||
| PubMed search | [3] | [4] | |||||||
| View/Edit Human | View/Edit Mouse |
Importin-7 is a protein that in humans is encoded by the IPO7 gene.[5][6]
The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical
ribosomal proteins.[6]
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000205339 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000066232 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- PMID 9214382.
- ^ a b "Entrez Gene: IPO7 importin 7".
Further reading
- Jäkel S, Görlich D (1998). "Importin beta, transportin, RanBP5 and RanBP7 mediate nuclear import of ribosomal proteins in mammalian cells". EMBO J. 17 (15): 4491–4502. PMID 9687515.
- Paraskeva E, Izaurralde E, Bischoff FR, Huber J, Kutay U, Hartmann E, Lührmann R, Görlich D (1999). "CRM1-mediated recycling of snurportin 1 to the cytoplasm". J. Cell Biol. 145 (2): 255–264. PMID 10209022.
- Jäkel S, Albig W, Kutay U, Bischoff F, Schwamborn K, Doenecke D, Görlich D (1999). "The importin beta/importin 7 heterodimer is a functional nuclear import receptor for histone H1". EMBO J. 18 (9): 2411–2423. PMID 10228156.
- Dean KA, von Ahsen O, Görlich D, Fried HM (2001). "Signal recognition particle protein 19 is imported into the nucleus by importin 8 (RanBP8) and transportin". J. Cell Sci. 114 (Pt 19): 3479–85. PMID 11682607.
- Bäuerle M, Doenecke D, Albig W (2002). "The requirement of H1 histones for a heterodimeric nuclear import receptor". J. Biol. Chem. 277 (36): 32480–32489. PMID 12080050.
- Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–16903. PMID 12477932.
- Gevaert K, Goethals M, Martens L, Van Damme J, Staes A, Thomas GR, Vandekerckhove J (2004). "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides". Nat. Biotechnol. 21 (5): 566–569. S2CID 23783563.
- Fassati A, Görlich D, Harrison I, Zaytseva L, Mingot JM (2003). "Nuclear import of HIV-1 intracellular reverse transcription complexes is mediated by importin 7". EMBO J. 22 (14): 3675–3685. PMID 12853482.
- Bouwmeester T, Bauch A, Ruffner H, Angrand PO, Bergamini G, Croughton K, Cruciat C, Eberhard D, Gagneur J (2004). "A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway". Nat. Cell Biol. 6 (2): 97–105. S2CID 11683986.
- King FW, Shtivelman E (2004). "Inhibition of nuclear import by the proapoptotic protein CC3". Mol. Cell. Biol. 24 (16): 7091–7101. PMID 15282309.
- Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–2127. PMID 15489334.
- Rush J, Moritz A, Lee KA, Guo A, Goss VL, Spek EJ, Zhang H, Zha XM, Polakiewicz RD (2005). "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells". Nat. Biotechnol. 23 (1): 94–101. S2CID 7200157.
- Kahle J, Baake M, Doenecke D, Albig W (2005). "Subunits of the heterotrimeric transcription factor NF-Y are imported into the nucleus by distinct pathways involving importin beta and importin 13". Mol. Cell. Biol. 25 (13): 5339–5354. PMID 15964792.
- Arnold M, Nath A, Hauber J, Kehlenbach RH (2006). "Multiple importins function as nuclear transport receptors for the Rev protein of human immunodeficiency virus type 1". J. Biol. Chem. 281 (30): 20883–20890. PMID 16704975.
- Zaitseva L, Myers R, Fassati A (2007). "tRNAs promote nuclear import of HIV-1 intracellular reverse transcription complexes". PLOS Biol. 4 (10): e332. PMID 17020411.
- Saijou E, Itoh T, Kim KW, Iemura Si, Natsume T, Miyajima A (2007). "Nucleocytoplasmic shuttling of the zinc finger protein EZI Is mediated by importin-7-dependent nuclear import and CRM1-independent export mechanisms". J. Biol. Chem. 282 (44): 32327–32337. PMID 17848547.
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