Jean Langhorne

Add links
Source: Wikipedia, the free encyclopedia.
Jean Langhorne
Alma materBedford College, London
Medical Research Council (United Kingdom)
Scientific career
InstitutionsFrancis Crick Institute
National Institute for Medical Research
National Institute of Allergy and Infectious Diseases
Imperial College London
ThesisStudies on antibodies in infectious mononucleosis (1979)

Jean Langhorne is a British biologist who is a group leader at the

Trends in Immunology
.

Early life and education

Langhorne completed her undergraduate degree in zoology at Bedford College, London.[1] She moved to the London School of Hygiene and Tropical Medicine for graduate research.[citation needed] Langhorne was a doctoral researcher at the Medical Research Council, where she investigated antibodies in mononucleosis.[2] She was a postdoctoral researcher at Guy's Hospital, where she worked alongside Sydney Cohen. Langhorne joined the Basel Institute for Immunology as a research associate. She was named a Fogarty Fellow at the National Institute of Allergy and Infectious Diseases.[1]

Research and career

Langhorne launched her independent scientific career at the Max Planck Institute of Immunobiology and Epigenetics.[3] She returned to the United Kingdom in 1995, where she joined the faculty at Imperial College London.[3] In 1998, Langhorne joined the National Institute for Medical Research. Her career has focused on understanding and eliminating pathogenic immune responses to malaria.[4][5] She has investigated how infections are eliminated from blood, and if it is possible to prevent severe malaria by blocking the pathological effects of the body's immune response.[6]

Langhorne has studied children who are constantly exposed to malaria during their childhood in Africa. Whilst some develop immunity to the disease, some are frequently infected. These investigations could help to design new therapeutics or uncover biomarkers for susceptibility.[6]

In recognition of her leadership in malaria researcher, Langhorne was awarded the EMBO-BioMalPar Lifetime Achievement Award in 2016.[7] On being awarded the prize, Langhorne said: "I am not finished yet! I still have a lot that I would like to do,".[7]

Awards and honours

  • 2015 Wellcome Trust Senior Investigator Award[8]
  • 2016 EMBO-BioMalPar Lifetime Achievement Award[7]

Selected publications

  • Jean Langhorne; Francis M Ndungu; Anne-Marit Sponaas;
    Wikidata Q37194482
    .
  • Morris HR; Paxton T; Dell A; Langhorne J; Berg M; Bordoli RS; Hoyes J; Bateman RH (1 January 1996). "High sensitivity collisionally-activated decomposition tandem mass spectrometry on a novel quadrupole/orthogonal-acceleration time-of-flight mass spectrometer".
    Wikidata Q71455987
    .
  • Alister G Craig; Georges E Grau; Chris Janse; James W Kazura; Dan Milner; John W Barnwell; Gareth Turner; Jean Langhorne (February 2012). "The role of animal models for research on severe malaria".
    Wikidata Q27348351
    .

References

  1. ^ a b "Jean Langhorne – Africawomenstem". Retrieved 2022-12-05.
  2. ^ "Studies on antibodies in infectious mononucleosis | WorldCat.org". www.worldcat.org. Retrieved 2022-12-05.
  3. ^ a b "Jean Langhorne". Crick. Retrieved 2022-12-05.
  4. ^ "The Medical Research Council's Review of the Future of the National Institute for Medical Research" (PDF). 2005-01-26.
  5. S2CID 205374119
    .
  6. ^ a b "Jean Langhorne". Crick. Retrieved 2022-12-05.
  7. ^ a b c "Prestigious Lifetime Achievement Award for Crick scientist Jean Langhorne". Crick. Retrieved 2022-12-05.
  8. ^ "The pir gene family: chronic infection, immunity and virulence". Wellcome. Retrieved 2022-12-05.
Retrieved from "https://en.wikipedia.org/w/index.php?title=Jean_Langhorne&oldid=1188626570"