Jesse Francis McClendon
Jesse Francis McClendon | |
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| Born | December 21, 1880 Hahnemann Medical College , Albert Einstein Medical Center |
Jesse Francis McClendon (December 21, 1880 – November 22, 1976) was an American
.McClendon made substantial contributions in a variety of fields, including
During the early 1930s, McClendon tested the healthfulness of hamburgers by putting a University of Minnesota medical student on a diet of only hamburgers and water for thirteen weeks.[5]
Biography
McClendon was born in
From 1907 to 1910, McClendon taught biology at
From 1910 to 1914, McClendon was an assistant instructor in histology and embryology at the
During this time (in 1911), he married and began a family. He and his wife ultimately had two children.
From 1910 to 1939, McClendon worked at the Physiological Laboratory of the University of Minnesota Medical School, Minneapolis, serving as professor of Physiological Chemistry between 1920 and 1939. During this time (in 1936), he married a second time.
It was also while working in this laboratory that McClendon achieved pioneering research, including his investigation of the relationsp between low iodine and goiter.[10] and Micromanipulation—Frog egg development.
Description of McClendon pH-probe
In measuring the acidity of the gastric contents, it was found possible to lower an electrode into the stomach. The apparatus designed for work on the stomach contents consists chiefly of a rubber tube 60 cm. long and 3 mm. bore, and two No. 40 silk covered
KCl solution, C, is placed, and the rest of the glass tube packed with moist KC1 crystals, D, and the hole, E, stuffed with cotton soaked in KC1 solution. This forms a calomel electrode, and is separated off from the remainder of the tube by a short piece of glass rod, F. Above F several holes are cut in the rubber tube at the level of G, and from this point a fine platinized platinum wire extends through the lumen of the tube and is held in place by fusion to a bump on the inside of a short piece of glass tube at the level of I. This platinum wire then connects with the wire M and the junction is coated with rubber. The rubber tube is connected at K with a tube, L, leading from a hydrogen generator, and a slow stream of H2 passes down the rubber tube and out at G, thus converting the platinum wire from H to F into a hydrogen electrode.[11]
Death
McClendon died on November 22, 1976, in Harleysville, Pennsylvania.
References
- ^ McClendon J. F. A direct reading potenciometer for measuring hydrogen ion concentration. Amer. J. Physiol., 1915, 38, 2, 186.
- ^ McClendon J. F. Acidity curves in the stomachs and duodenums of adults and infants plotted with the acid of imported methods of measuring hydrogen ion concentration. Amer. J. Physiol., 1915, 38, 2, 191.
- Ben Karpman. The hydrogen ion concentrations of the contents of the small intestine. J. of Biological Chemistry, Feb 19, 1918. XXXIV, No 1.
- ^ University of Minnesota Archives.
- ^ "An unusual hamburger experiment is part of the University of Minnesota's dietary research annals. Medical Bulletin. 2008, winter issue. Minnesota Medical Foundation". Archived from the original on 2008-08-04. Retrieved 2008-05-29.
- ^ McClendon J. F. Bulletin American Museum of Natural History. Vol. XXII, 1906, p. 119.
- .
- ^ Cornell University Information Database. Archived 2008-09-07 at the Wayback Machine
- ^ Pynes Ch. Al.. Human Cloning and Moral Status. The Florida State University, 2003.
- ^ McClendon J. F. The distribution of iodine with special reference to goiter. Physiol Rev, Apr 1927; 7: 189–258.
- ^ McClendon J. F. New hydrogen electrodes and rapid methods of determining hydrogen ion concentrations. Amer. J. Physiol., 1915, 38, 2, 180.
External links
- Works by or about Jesse Francis McClendon at Internet Archive
- Jesse F. McClendon papers, 1910s-1960s. University of Minnesota Archives
- The Portrait of J.F.McClendon on 1905
- Minneapolis Department. History
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