Karl Slotta

Source: Wikipedia, the free encyclopedia.
Karl Slotta
Born(1895-05-12)May 12, 1895
Breslau, Germany (now Wrocław, Poland)
DiedJuly 17, 1987(1987-07-17) (aged 92)
SpouseMaja Slotta
Academic background
Alma materUniversity of Breslau
Academic work
DisciplineChemistry
Sub-disciplinebiochemistry
InstitutionsChemical Institute in Breslau, Germany,
Chemistry Institute of the University of Vienna,
Instituto Butantan,
University of Miami
Notable ideasoral contraceptive pills

Karl Heinrich Slotta (May 12, 1895 in

birth control pills.[1]

Life

Slotta was drafted into military service in

University of Breslau in 1923 where he discovered that the biguanided metformin lowers the blood glucose concentration in rabbits.[2]
He continued post-doc work at the university with guidance from Professor Fraenkel.

In 1933, Slotta was first, or one of the first, to isolate and identify progesterone (there being four separate research labs which claim such distinction).

In 1934, he proposed a correct

Nazis
. As persecution escalated, in 1935 he left Germany with his family for the safety of Brazil.

In Brazil, Slotta initially worked on the chemistry of coffee, from which bean oil he extracted a substance he called "cafestol" that he reported had estrogenic properties. As a result, European

lipids. He subsequently co-founded a biopharmaceutical company.[3]

On May 3, 1948, Slotta traveled from Santos, Brazil aboard the steamer, S.S. Argentina, arriving in at the Port of New York, May 17, 1948, with his wife Maja Slotta, and daughter.

They were bound for Berkeley, California, where Maja's brother, Heinz had relocated.

After moving to Miami, Florida with his wife and son in the 1956, Slotta unsuccessfully looked for a polio cure using venom.[4] Slotta purified the most basic polypeptide from

cardiotoxin
.

In 1956, Slotta was appointed research professor of biochemistry at the University of Miami, Florida. Slotta became a naturalized United States citizen March 30, 1961 in Miami, Florida.

Family

On July 16, 1927, Karl Slotta married Maja Fraenkel, PhD, daughter of Professor Ludwig Fraenkel (1870–1951) and Lili Conrat, in Breslau, Germany.

Ludwig Fraenkel was a prominent gynecologist and medical researcher in Breslau, Germany. Fraenkel's daughter, Maja Fraenkel (Slotta) was an economist, talented pianist, and author of a paper, published in 1928 addressing Zur Frage der psychotechnischen Eignungsprüfung für den Chemikerberuf.

The couple met through Slotta's work with Professor Frankel.

Maja at the time was associated with the Psychotechnisches Institute beim Berufsami der Stadt Breslau. Her own career as a researcher was largely redirected to a supportive role after the birth of two children.

After immigration to the United States, in Miami, in 1956 she was an early organizer of the Medical Faculty Wives Medical Student Loan Fund, established under auspices of the Medical Faculty Association of the University of Miami (of which her husband was a member, as research professor of biochemistry and medicine). Maja Slotta identified and secured Federal funds that matched donations nine to one, thereby facilitating the early growth of this fund. Providing funds and assistance to the medical students became the primary endeavor of the group. The project has since grown into a successful scholarship endowment. Maja resumed research after raising her children and was co-author of a 1961 study on The Impact of Airports on the Economy of Southeastern Florida, published by University of Miami Bureau of Business and Economic Research.

Maja Fraenkel's brother was the biochemist Heinz Fraenkel-Conrat (1910–1999).

References

  1. ^ Associated Press. "Birth control pioneer Karl Slota is dead". Gainesville Sun. Retrieved 2016-03-20.
  2. .
  3. ^ Hawgood, Babara J.,Karl Heinrich Slotta (1895–1987) Biochemist: Snakes, Pregnancy and Coffee, Toxicon, Volume 39, Issue 9, September 2001, Pages 1277–1282.
  4. ISSN 0362-4331
    . Retrieved 2016-03-20.

Sources