MCI Screen
 | This article contains promotional content. (April 2014) |
| MCI Screen | |
|---|---|
| Purpose | check mild cognitive impairment |
The MCI Screen is a brief neuropsychological test checking for mild cognitive impairment (MCI).
The protocol consists of an immediate recall task, a triadic comparison task, a judgment task, a delayed free recall task, a cued-recall task, and a rehearsed recall task. It is scored using
cognitive function from Mild cognitive impairment. The methodology for scoring the MCI Screen was developed by the Embic Corporation
(formerly Medical Care Corporation), a privately held California Corporation.
It was derived from the protocol of the CERAD 10-word recall test.
Validation
The MCI Screen was validated in a study on 471 community dwelling adults whose scores on the
Clinical Dementia Rating Scale ranged from 0 (normal: N=119), 0.5 (mild cognitive impairment: N=95), to 1 (mild dementia: N=257). According to a 2005 publication in The Proceedings of the National Academy of Sciences, the MCI Screen has overall accuracy of 98% with sensitivity of 97% for mild cognitive impairment or mild dementia, and 88% specificity for normal aging.[1] Clinical studies in the USA have shown that the MCI Screen detects early-stage, memory loss due to multiple underlying medical conditions including Alzheimer's disease, cerebrovascular disease, and others.[2] Japan based studies have demonstrated cross-cultural validity of the MCI Screen in clinical and academic settings with accuracy levels equal to those in the USA.[3][4]
References
- ^ Shankle WR, Romney AK, Hara J, et al. Method to improve the detection of mild cognitive impairment. PNAS. 2005; 102(13): 4919-24.
- ^ Trenkle D, Shankle WR, Azen SP. Detecting Cognitive Impairment in Primary Care: Performance Assessment of Three Screening Instruments. Journal of Alzheimer's Disease. 2007; 11(3):323-335.
- ^ Ai Cho, Mika Sugimura, Seigo Nakano, Tatsuo Yamada. Early Detection and Diagnosis of Demented Disorders Using the MCI Screen and Neuroimaging; The Japanese Journal of Clinical and Experimental Medicine. 2007; 84(8):1152-1160.
- ^ Ai Cho; Mika Sugimura; Seigo Nakano, Tatsuo Yamada. The Japanese MCI Screen for Early Detection of Alzheimer’s Disease and Related Disorders. The American Journal of Alzheimer’s Disease and Other Dementias. 2008; June/July (in press).