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Non-coding RNA in the species Homo sapiens
Wikidata MicroRNA 7-1 is a microRNA molecule that in humans is encoded by the MIR7-1 gene .[3]
Function This section
may contain material )
base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The
RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009].
References Further reading
Lim LP, Glasner ME, Yekta S, Burge CB, Bartel DP (March 2003). "Vertebrate microRNA genes". Science . 299 (5612): 1540. . Correa-Medina M, Bravo-Egana V, Rosero S, Ricordi C, Edlund H, Diez J, Pastori RL (April 2009). "MicroRNA miR-7 is preferentially expressed in endocrine cells of the developing and adult human pancreas". Gene Expression Patterns . 9 (4): 193–9. . Chen AX, Yu KD, Fan L, Li JY, Yang C, Huang AJ, Shao ZM (September 2011). Horwitz MS (ed.). "Germline genetic variants disturbing the Let-7/LIN28 double-negative feedback loop alter breast cancer susceptibility" . PLOS Genetics . 7 (9): e1002259. . Xu L, Wen Z, Zhou Y, Liu Z, Li Q, Fei G, Luo J, Ren T (January 2013). "MicroRNA-7-regulated TLR9 signaling-enhanced growth and metastatic potential of human lung cancer cells by altering the phosphoinositide-3-kinase, regulatory subunit 3/Akt pathway" . Molecular Biology of the Cell . 24 (1): 42–55. . Kefas B, Godlewski J, Comeau L, Li Y, Abounader R, Hawkinson M, Lee J, Fine H, Chiocca EA, Lawler S, Purow B (May 2008). "microRNA-7 inhibits the epidermal growth factor receptor and the Akt pathway and is down-regulated in glioblastoma" . Cancer Research . 68 (10): 3566–72. . Bravo-Egana V, Rosero S, Molano RD, Pileggi A, Ricordi C, Domínguez-Bendala J, Pastori RL (February 2008). "Quantitative differential expression analysis reveals miR-7 as major islet microRNA" . Biochemical and Biophysical Research Communications . 366 (4): 922–6. . Chen ZX, Sun AM, Chen Y, Liu Y, Zhan JF, Chen LH, Yuan YW (August 2010). "[Effects of radiosensitivity and X-ray dose on miR-7 expression in nasopharyngeal carcinoma]". Nan Fang Yi Ke da Xue Xue Bao = Journal of Southern Medical University . 30 (8): 1810–2, 1816. . Kredo-Russo S, Ness A, Mandelbaum AD, Walker MD, Hornstein E (2012). "Regulation of pancreatic microRNA-7 expression" . Experimental Diabetes Research . 2012 : 695214. . Wang Y, Liu J, Liu C, Naji A, Stoffers DA (March 2013). "MicroRNA-7 regulates the mTOR pathway and proliferation in adult pancreatic β-cells" . Diabetes . 62 (3): 887–95. . Midgley AC, Bowen T, Phillips AO, Steadman R (April 2014). "MicroRNA-7 inhibition rescues age-associated loss of epidermal growth factor receptor and hyaluronan-dependent differentiation in fibroblasts" . Aging Cell . 13 (2): 235–44. . Midgley AC, Morris G, Phillips AO, Steadman R (June 2016). "17β-estradiol ameliorates age-associated loss of fibroblast function by attenuating IFN-γ/STAT1-dependent miR-7 upregulation" . Aging Cell . 15 (3): 531–41. .
This article incorporates text from the United States National Library of Medicine , which is in the public domain .
