MicroRNA let-7f-2 is a protein that in humans is encoded by the MIRLET7F2 gene.
[3]
Function
Dicer ribonuclease
to generate the mature miRNA and antisense miRNA star (miRNA*) products.
The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009].
Yan S, Han X, Xue H, Zhang P, Guo X, Li T, Guo X, Yuan G, Deng L, Li G (2015). "Let-7f Inhibits Glioma Cell Proliferation, Migration, and Invasion by Targeting Periostin". J. Cell. Biochem. 116 (8): 1680โ92.