Mihaela Zavolan
Mihaela Zavolan | |
---|---|
Victor Babeș University of Medicine and Pharmacy, Timișoara, University of New Mexico, Santa Fe Institute, Los Alamos National Laboratory, Rockefeller University, Swiss Institute of Bioinformatics, Biozentrum University of Basel |
Mihaela Zavolan is a system biologist and Professor at the Biozentrum of the University of Basel.
Life
Mihaela Zavolan studied medicine at the
Work
The main focus of the research in Mihaela Zavolan's group is of microRNAs (miRNAs).[3] These 22 nucleotides long RNA molecules regulate the expression of protein coding genes, thereby controlling cell differentiation, metabolism and immune responses. Through the development of high-throughput experimental methods and computational analyses, Zavolan has contributed to the discovery of many miRNAs in various organisms ranging from viruses to humans.[4] She has developed algorithms to predict miRNA genes and miRNA targets, and has worked on the development of the CLIP method (cross-linking and immunoprecipitation) for mapping the binding sites of RNA-binding proteins in RNAs.[5] Recently, her group used CLIP binding site data to infer a biophysical model of miRNA-target interaction, which can be used to predict the strength between of interactions between miRNAs and their targets on mRNAs and long non-coding RNA.[6]
Awards and honors
- 2012 ERC Starting Grant[7][8]
- 2014 elected Member of the Academia Europaea[9]
References
- ^ "Curriculum Vitae". Biozentrum.unibas.ch. Retrieved 2014-01-27.
- ^ "SIB Group M. Zavolan". isb-sib.ch. Retrieved 2014-01-27.
- ^ "Research Group Mihaela Zavolan". eurasnet.info. Archived from the original on 2015-05-26. Retrieved 2014-01-27.
- ^ "New biophysical model predicts regulation by microRNAs". biozentrum.unibas.ch. Retrieved 2014-01-27.
- S2CID 5313093.
- S2CID 205421282.
- ^ "ERC Starting Grant for Mihaela Zavolan". biozentrum.unibas.ch. Retrieved 2014-01-27.
- ^ "Success for HFSP alumni in the latest competition for ERC Starting Grants". hfsp.org. Retrieved 2014-01-27.
- ^ Elected Member of the Academia Europaea ae-info.org. Retrieved 2014-9-04
External links
Video link
- Video: Prof. Dr. Mihaela Zavolan – Computational Biology cccs.unibas.ch. Retrieved 2020-12-21