Mostafa Ronaghi
Mostafa Ronaghi (
As of 2008[update], he is the Chief Technology Officer and Senior Vice President at
He is principal investigator for several grants including grants from the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health[2] for the development of array-based Pyrosequencing.
In 1998, he described together with Pål Nyren and Mathias Uhlen[3] a solution-based variant of the pyrosequencing technology and co-founded Pyrosequencing AB (renamed to Biotage in 2003). He co-invented Molecular Inversion Probe assay and co-founded ParAllele BioScience to develop this multiplexed technology for genetic testing. ParAllele was acquired by Affymetrix in May 2005. In 2005, he co-founded
Publications
Among his approximately 50 peer-reviewed journal articles are the publications describing Pyrosequencing and Molecular Inversion Probe assays and other techniques:
- Absalan, F; Ronaghi, M (2007). Molecular inversion probe assay. PMID 18025701.
- Hardenbol, P; Banér, J; Jain, M; Nilsson, M; Namsaraev, EA; Karlin-Neumann, GA; Fakhrai-Rad, H; Ronaghi, M; Willis, TD; Landegren, U; Davis, RW (Jun 2003). "Multiplexed genotyping with sequence-tagged molecular inversion probes". S2CID 17619191.
- Talasaz, AH; Nemat-Gorgani, M; Liu, Y; et al. (Oct 2006). "Prediction of protein orientation upon immobilization on biological and nonbiological surfaces". PMID 17001006.
- Ronaghi, M (Jan 2001). "Pyrosequencing sheds light on DNA sequencing". PMID 11156611.
- Ronaghi, M; Uhlén, M; Nyrén, P (Jul 1998). "A sequencing method based on real-time pyrophosphate". S2CID 26331871.
- Ronaghi, M; Karamohamed, S; Pettersson, B; Uhlén, M; Nyrén, P (Nov 1996). "Real-time DNA sequencing using detection of pyrophosphate release". PMID 8923969.
He also holds about 20 patents.
References
- ^ "Illumina | 2008 Release: Illumina Appoints Mostafa Ronaghi as Senior Vice President and Chief Technology Officer". Archived from the original on 2008-10-03. Retrieved 2008-08-04.
- ^ genome.gov | 2004 Release: NHGRI Seeks Next Generation of Sequencing Technologies
- S2CID 26331871.
- ^ "Illumina | Illumina Signs Agreement to Acquire NextBio, Leader in Analyzing and Aggregating Complex Genomic Data". Archived from the original on 2014-12-26. Retrieved 2014-02-12.
- ^ tradingmarkets.com | 2008 Release: Illumina To Acquire Privately-Held Avantome For $25 Million In Cash Upfront[dead link]
- ^ Carroll, John (23 Jul 2008). "Illumina snares sequencing tech in $60M buyout". fiercebiotech.com. Questex, LLC. Retrieved 19 Oct 2019.
- [Pyrosequencing Array for DNA Sequencing]