Mouse brain

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Mouse brain, lateral view

The mouse brain refers to the

Mus musculus. Various brain atlases
exist.

For reasons of reproducibility, genetically characterized, stable strains like C57BL/6 were chosen to produce high-resolution images and databases.[1] Well known online resources include:

Despite superficial differences, especially in size and weight, the mouse brain and its function can serve as a powerful

diseases or mental disorders (see e.g. Reeler, Chakragati mouse). This is because the genes responsible for building and operating both mouse and human brain are 90% identical.[4] Transgenic mouse lines also allow neuroscientists to specifically target the labeling of certain cell types to probe the neural basis of fundamental processes.[5][6]

Anatomy

The cerebral cortex of a mouse has around 8–14 million neurons while in those humans there are more than 10–15 billion.[7][8] The olfactory bulb volume takes about 2% of the mouse brain by volume in contrast to about 0.01% of the human brain.[9][10]

  • Mouse brain, dorsal view
    Mouse brain, dorsal view
  • Mouse brain, lateral view
    Mouse brain, lateral view
  • Mouse brain slices
    Mouse
    brain slices
  • Mouse cingulate cortex neurons
    Mouse cingulate cortex neurons
  • A biophysically realistic model of the mouse primary motor cortex microcircuit representing a cylindrical volume of 300 μm diameter: 3D visualization, connectivity, dimensions, and neuronal densities, classes, and morphologies[11]
    A biophysically realistic model of the mouse primary motor cortex microcircuit representing a cylindrical volume of 300 μm diameter: 3D visualization, connectivity, dimensions, and neuronal densities, classes, and morphologies[11]

Development

See also

References

  1. S2CID 81057
    .
  2. ^ "ISH Data :: Allen Brain Atlas: Mouse Brain". ISH Data. Retrieved 2019-02-07.
  3. ^ "Search the library". The Mouse Brain Library. 2003-06-05. Retrieved 2019-02-07.
  4. ^ Park, Alice (19 January 2007). "The Brain: What the Mouse Brain Tells Us". Time.
  5. PMID 6261253
    .
  6. PMID 19283728
    .
  7. ^ "Brain size and intelligence- why a human is smarter than a mouse". DNALC Blogs «. 2012-11-13. Retrieved 2019-02-07.
  8. PMID 26418466
    .
  9. PMID 28495701
    .
  10. ^ "Brain Facts and Figures". faculty.washington.edu. Retrieved 2019-02-07.
  11. doi:10.1016/j.celrep.2023.112574
    . Retrieved 21 June 2023.
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