Multisystem developmental disorder
Appearance
Multisystem developmental disorder (MSDD) is a term used by Stanley Greenspan to describe children under age 3 who exhibit signs of impaired communication as in autism, but with strong emotional attachments atypical of autism.[citation needed] It is described in the DC:0-3R manual as an optional diagnosis for children under two years of age.[1][2]
Other uses of the term
The term multisystem developmental disorder has also been used to describe various developmental disorders. These include:
- Alagille syndrome,[3] an autosomal dominant disorder with a wide range of features and manifestations. Its five most significant features are chronic cholestasis, a condition where bile cannot flow from the liver to the duodenum, occurring in 95% of cases; heart abnormalities (over 90%); butterfly vertebrae; posterior embryotoxon and a distinctive face (prominent forehead, deep-set eyes, and a pointed chin).[4]
- Williams syndrome,[8][9] a neurodevelopmental disorder characterized by a unique profile of strengths and deficits; most with the condition have mild intellectual disability but have grammatical and lexical abilities above what would be expected from their IQs.[10] They are hypersocial and empathetic, but social isolation is commonly experienced.[11]
- Proteus syndrome,[12] a congenital disorder causing disproportionate growth of skin, bone, and other tissues.[13]
- Asphyxiating thoracic dysplasia,[14] an autosomal recessive skeletal disorder with an estimated prevalence of between 1 in 100,000 and 1 in 130,000 live births.[15]
Symptoms
- Toe walking[16]
- Pragmatic speech problems[16]
- Clumsiness[16]
- Obsessions and rituals[16]
- Sensory issues[16]
- Disinterest in social interaction[16]
- Autistic characteristics[16]
References
- PMID 21142337.
- PMID 17907517.
- PMID 12244552.
- PMID 21934706.
- PMID 8726717.
- ^ "Rubinstein-Taybi syndrome: MedlinePlus Genetics".
- PMID 3629765.
- S2CID 12793159.
- S2CID 41861608.
- ISBN 978-0-8058-1180-3.
- ISBN 978-0-8018-8212-8.
- PMID 22514103.
- PMID 23024722.
- PMID 12807964.
- S2CID 33532185.
- ^ a b c d e f g Woliver, Robbie (2009). Alphabet Kids. Jessica Kingsley Publishers. p. 295.
Further reading
- Scheeringa, MS (2001). "The differential diagnosis of impaired reciprocal social interaction in children: A review of disorders". Child Psychiatry and Human Development. 32 (1): 71–89. S2CID 43311652.
- Increasing Interaction with Children with Multisystem Developmental Disorder (MSDD), Developmental Delay Resources
- Wieder, S (1996). "Integrated treatment approaches for young children with multisystem developmental disorder". Infants & Young Children. 8 (3): 24–34. S2CID 145177134.