NLRC3
Ensembl | |||||||||
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| UniProt | |||||||||
| RefSeq (mRNA) | |||||||||
| RefSeq (protein) | |||||||||
| Location (UCSC) | Chr 16: 3.54 – 3.58 Mb | Chr 16: 3.76 – 3.79 Mb | |||||||
| PubMed search | [3] | [4] | |||||||
| View/Edit Human | View/Edit Mouse |
NLRC3, short for
intracellular protein that plays a role in the immune system.[5] It was previously known as nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 3 (NOD3) and CLR16.2. NLRC3 inhibits the activity of T cells.[6] NLRC3 also inhibits the mTOR signalling pathway to block cellular proliferation.[7]
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000167984 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000049871 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- PMID 18341998.
- PMID 15705585.
- PMID 27951586.