Nemosis
Nemosis is a process of cell activation and death in human fibroblasts.[1][2][3][4] Initially discovered as programmed
diploid fibroblasts induce cell activation leading to programmed cell death, PCD. This type of PCD has features of necrosis rather than apoptosis
.
Nemosis of fibroblasts, or
prostaglandins,[2] as well as growth factors such as hepatocyte growth factor.[1] It is thus indicated to contribute to processes like acute and chronic inflammation, and cancer
. Factors secreted by nemotic fibroblasts also
break down the ECM. Such factors include several matrix metalloproteinases,[3] and plasminogen activation.[2]
References
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