PCYT1A
| PCYT1A | |||
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Gene ontology | |||
| Molecular function | |||
| Cellular component | |||
| Biological process | |||
| Sources:Amigo / QuickGO | |||
Ensembl | |||||||||
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| RefSeq (protein) | |||||||||
| Location (UCSC) | Chr 3: 196.21 – 196.29 Mb | Chr 16: 32.25 – 32.29 Mb | |||||||
| PubMed search | [3] | [4] | |||||||
| View/Edit Human | View/Edit Mouse |
Choline-phosphate cytidylyltransferase A is an enzyme that in humans is encoded by the PCYT1A gene.[5][6]
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000161217 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000005615 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- PMID 7918629.
- ^ "Entrez Gene: PCYT1A phosphate cytidylyltransferase 1, choline, alpha".
Further reading
- Hunt AN, Normand CS, Postle AD (1990). "CTP:cholinephosphate cytidylyltransferase in human and rat lung: association in vitro with cytoskeletal actin". Biochim. Biophys. Acta. 1043 (1): 19–26. PMID 2155660.
- Vance JE, Vance DE (1988). "Does rat liver Golgi have the capacity to synthesize phospholipids for lipoprotein secretion?". J. Biol. Chem. 263 (12): 5898–909. PMID 2833521.
- Weinhold PA, Feldman DA (1995). "Fatty acids promote the formation of complexes between choline-phosphate cytidylyltransferase and cytidylyltransferase binding protein". Arch. Biochem. Biophys. 318 (1): 147–56. PMID 7726555.
- Johnson JE, Cornell RB (1994). "Membrane-binding amphipathic alpha-helical peptide derived from CTP:phosphocholine cytidylyltransferase". Biochemistry. 33 (14): 4327–35. PMID 8155650.
- Dunne SJ, Cornell RB, Johnson JE, et al. (1996). "Structure of the membrane binding domain of CTP:phosphocholine cytidylyltransferase". Biochemistry. 35 (37): 11975–84. PMID 8810902.
- Arnold RS, DePaoli-Roach AA, Cornell RB (1997). "Binding of CTP:phosphocholine cytidylyltransferase to lipid vesicles: diacylglycerol and enzyme dephosphorylation increase the affinity for negatively charged membranes". Biochemistry. 36 (20): 6149–56. PMID 9166786.
- Yang J, Wang J, Tseu I, et al. (1997). "Identification of an 11-residue portion of CTP-phosphocholine cytidylyltransferase that is required for enzyme-membrane interactions". Biochem. J. 325. ( Pt 1) (Pt 1): 29–38. PMID 9224626.
- Lykidis A, Baburina I, Jackowski S (1999). "Distribution of CTP:phosphocholine cytidylyltransferase (CCT) isoforms. Identification of a new CCTbeta splice variant". J. Biol. Chem. 274 (38): 26992–7001. PMID 10480912.
- Lagace TA, Miller JR, Ridgway ND (2002). "Caspase processing and nuclear export of CTP:phosphocholine cytidylyltransferase alpha during farnesol-induced apoptosis". Mol. Cell. Biol. 22 (13): 4851–62. PMID 12052891.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. PMID 12477932.
- Guenther MG, Yu J, Kao GD, et al. (2003). "Assembly of the SMRT-histone deacetylase 3 repression complex requires the TCP-1 ring complex". Genes Dev. 16 (24): 3130–5. PMID 12502735.
- Xie M, Smith JL, Ding Z, et al. (2004). "Membrane binding modulates the quaternary structure of CTP:phosphocholine cytidylyltransferase". J. Biol. Chem. 279 (27): 28817–25. PMID 15069071.
- Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. S2CID 14294292.
- Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. S2CID 7827573.
- Enaw JO, Zhu H, Yang W, et al. (2007). "CHKA and PCYT1A gene polymorphisms, choline intake and spina bifida risk in a California population". BMC Medicine. 4: 36. PMID 17184542.
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