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  • Thumbnail for Sirolimus
    Sirolimus (category Drugboxes which contain changes to watched fields)
    mammalian target of rapamycin (mTOR), capable of integrating signals from the PI3K/AKT pathway to coordinate proper cell growth and proliferation. Hence, sirolimus...
    68 KB (6,700 words) - 21:46, 24 April 2024
  • Thumbnail for Papillary hidradenoma
    Papillary hidradenoma (category CS1 French-language sources (fr))
    to the production of proteins that directly or indirectly stimulate the PI3K/AKT/mTOR intracellular signaling pathway. The mutated genes include PIK3CA...
    22 KB (2,440 words) - 21:14, 6 January 2024
  • Thumbnail for Cowpox
    Cowpox (category CS1 German-language sources (de))
    During the infection, CPXV is known to use MEK/ERK/1/2/Egr-1, JNK1/2, and PI3K/Akt pathways. Some of these pathways are not unique only to CPXV, but how they...
    35 KB (4,288 words) - 18:32, 27 April 2024
  • CKLF-like MARVEL transmembrane domain-containing 5 (category CS1 Chinese-language sources (zh))
    2022). "CMTM5 inhibits the development of prostate cancer via the EGFR/PI3K/AKT signaling pathway". Molecular Medicine Reports. 25 (1). doi:10.3892/mmr...
    15 KB (1,909 words) - 10:08, 8 January 2024
  • Thumbnail for Estrogen
    Estrogen (category Articles containing explicitly cited British English-language text)
    membrane-initiated steroid signalling, MISS). This pathway stimulates the ERK and PI3K/AKT pathways, which are known to increase cellular proliferation and affect...
    72 KB (7,575 words) - 07:57, 13 April 2024
  • Thumbnail for Platelet
    Platelet (category Articles containing Greek-language text)
    P2Y12 antagonists.[citation needed] Data suggest that ADP activates the PI3K/Akt pathway during a first wave of aggregation, leading to thrombin generation...
    70 KB (8,489 words) - 17:12, 12 April 2024
  • Thumbnail for Cancer treatment
    Cancer treatment (category CS1 German-language sources (de))
    S, O'Byrne KJ, Gately K (April 2014). "Strategies for co-targeting the PI3K/AKT/mTOR pathway in NSCLC". Cancer Treatment Reviews. 40 (3): 445–456. doi:10...
    70 KB (8,493 words) - 11:19, 26 February 2024
  • Thumbnail for Interleukin 6
    Interleukin 6 (category CS1 Polish-language sources (pl))
    modification within the brain. IL-6 activates the Phosphoinositide 3-kinase (PI3K) pathway, and a downstream target of this pathway is the protein kinase B...
    64 KB (7,427 words) - 18:57, 26 April 2024
  • Thumbnail for Buformin
    Buformin (category Articles with changed CASNo identifier)
    Frieman MB, et al. (February 2015). "Antiviral potential of ERK/MAPK and PI3K/AKT/mTOR signaling modulation for Middle East respiratory syndrome coronavirus...
    21 KB (2,257 words) - 20:46, 23 April 2024
  • Thumbnail for 5-HT2A receptor
    5-HT2A receptor (category CS1 German-language sources (de))
    "HTR2A promotes the development of cardiac hypertrophy by activating PI3K-PDK1-AKT-mTOR signaling". Cell Stress & Chaperones. 25 (6): 899–908. doi:10...
    88 KB (9,591 words) - 17:21, 21 April 2024